Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
| dc.contributor.author | Bronte, Vincenzo | |
| dc.contributor.author | Brandau, Sven | |
| dc.contributor.author | Chen, Shu-Hsia | |
| dc.contributor.author | Colombo, Mario P. | |
| dc.contributor.author | Frey, Alan B. | |
| dc.contributor.author | Greten, Tim F. | |
| dc.contributor.author | Mandruzzato, Susanna | |
| dc.contributor.author | Murray, Peter J. | |
| dc.contributor.author | Ochoa, Augusto | |
| dc.contributor.author | Ostrand-Rosenberg, Suzanne | |
| dc.contributor.author | Rodriguez, Paulo C. | |
| dc.contributor.author | Sica, Antonio | |
| dc.contributor.author | Umansky, Viktor | |
| dc.contributor.author | Vonderheide, Robert H. | |
| dc.contributor.author | Gabrilovich, Dmitry I. | |
| dc.date.accessioned | 2019-03-04T14:57:04Z | |
| dc.date.available | 2019-03-04T14:57:04Z | |
| dc.date.issued | 2016-07-06 | |
| dc.description.abstract | Myeloid-derived suppressor cells (MDSCs) have emerged as major regulators of immune responses in cancer and other pathological conditions. In recent years, ample evidence supports key contributions of MDSC to tumour progression through both immune-mediated mechanisms and those not directly associated with immune suppression. MDSC are the subject of intensive research with >500 papers published in 2015 alone. However, the phenotypic, morphological and functional heterogeneity of these cells generates confusion in investigation and analysis of their roles in inflammatory responses. The purpose of this communication is to suggest characterization standards in the burgeoning field of MDSC research. | en_US |
| dc.description.sponsorship | This work was supported by NIH grants CA 141438 and CA 084488 to D.I.G., GM021248 to S.O.-R., CA 184185 to P.C.R., grants from the Italian Ministry of Education, Universities and Research (FIRB cup: B31J11000420001; FIRB cup: RBAP11H2R9_005; PRIN cup: 20103FMJEN_003) to V.B. and A.S.; the Italian Association for Cancer Research (AIRC 6599, 12182, 12886, 14103, 14194, 14103 and 15585) and the Italian Ministry of Health (FINALIZZATA cup: E35G1400019001) to V.B., M.P.C., A.S., S.M.; Action BM1404 Mye-EUNITER supported by COST (European Cooperation in Science and Technology) to S.B. and V.U.; the German Research Association (DFG, grant 2278/2-1) to S.B., The American Lebanese Syrian Associated Charities of St. Jude Children’s Research Hospital and Cancer Center Core grant P30 CA21765 to P.M. and the DKFZ-MOST Cooperation in Cancer Research (CA157) to V.U. | en_US |
| dc.description.uri | https://www.nature.com/articles/ncomms12150 | en_US |
| dc.format.extent | 10 pages | en_US |
| dc.genre | journal articles | en_US |
| dc.identifier | doi:10.13016/m2jt6j-kkf8 | |
| dc.identifier.citation | Bronte, V. et al. Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards. Nat. Commun. 7:12150 doi: 10.1038/ncomms12150 (2016). | en_US |
| dc.identifier.uri | https://doi.org/10.1038/ncomms12150 | |
| dc.identifier.uri | http://hdl.handle.net/11603/12903 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Springer Nature Publishing AG | en_US |
| dc.relation.isAvailableAt | The University of Maryland, Baltimore County (UMBC) | |
| dc.relation.ispartof | UMBC Biological Sciences Department Collection | |
| dc.relation.ispartof | UMBC Faculty Collection | |
| dc.rights | This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author. | |
| dc.rights | Attribution 4.0 International (CC BY 4.0) | * |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | * |
| dc.subject | immunosuppression | en_US |
| dc.subject | Medical research | en_US |
| dc.subject | Myelopoiesis | en_US |
| dc.subject | Tumour immunology | en_US |
| dc.title | Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards | en_US |
| dc.type | Text | en_US |