Browsing by Author "Hayes, Collin"
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ItemEcological and Evolutionary Trends of Lyme disease in the Northeastern United States(2016) Hayes, Collin; Bachelor's DegreeWhen my biology professor first introduced our research assignment in class, I had no idea where to begin to look within the vast ocean of information that is the habitat for the subjects of ecology and evolution. I could have written my paper on almost any existent life form, but I had to pursue it with a depth and specificity of research that would amount to writing proficiency in the biology major, a daunting task to say the least. On top of this, the research assignment was to be in the form of a review paper, a comprehensive analysis of primary literature, unlike any lab report I had written before. There was no methods section to guide me; instead there was only my own inspiration and Goucher’s library services. The subject of my review paper came to me in a rather peculiar way. I was speaking to my distant great aunt at my great grandmother’s funeral when she brought up the subject that Lyme Disease may have contributed to my grandfather’s death years ago. My great aunt happened to be conducting holistic research in various chronic diseases across the US and I began my research by posing her a series of questions that led to an online query in Goucher’s Biological Abstracts and Academic Search Complete library databases. After spending two weeks reviewing the latest research from experts on tick ecology and Lyme Disease evolution and ordering articles from the interlibrary loan service, I amassed enough information to synthesize the story of Lyme Disease in the Northeastern US. Not only was I able to isolate fascinating pertinent information using the library’s databases, but I also learned how to manage my way through the scientific community, an invaluable lesson since I aim to one day contribute to this same community. ItemGymnema Sylvestre: An Ancient Herbal Remedy for Diabetes Mellitus(2015) Hayes, Collin; Bachelor's Degree ItemHelicobacter pylori and the Development of Gastric Cancer(2016) Hayes, Collin; Bachelor's DegreeMy research was inspired by a close friend who has Crohn’s Disease. This autoimmune disorder causes chronic bowel inflammation resulting in irritable bowel disease, diarrhea, and malnutrition. Although there is no cure, current treatment uses antibiotics, corticosteroids, and immunosuppressants to alleviate most symptoms. Originally assigned to write a review paper for my microbiology and immunology course, I wanted to research the latest literature in potential groundbreaking treatments for Crohn’s Disease that may lead to developing a cure. Ultimately, I found very little save for the multitude of studies on current treatments. One of the most intriguing studies I found using Goucher’s library database Biological Abstracts related the development of Crohn’s Disease to infection with a particular gram negative stomach bug called Helicobacter pylori. However, despite this correlation to an infectious bacteria, there was no explanation of how or why H. pylori was associated with this autoimmune disorder. Having run into a dead end, I began researching the ways in which H. pylori induces gastric cancer specifically because this virulent method of inducing cancer comprises five percent of the world’s cancer burden. I was amazed at how much research was devoted to this field of study and I was able to access the majority of my research articles for free using Bio One, Biological Abstracts, and PubMed. The few articles I could not immediately access, I was able to receive in a few days through Goucher’s interlibrary loan service. Although I was ultimately unable to achieve my original goal of researching advancements into the treatment of Crohn’s Disease, I explored the potential mechanisms of eradication of gastric cancer and H. pylori, which may reduce the incidence of Crohn’s Disease. Overall, my research method using Goucher’s databases taught me to be patient and to explore alternate mechanisms when the first doesn’t work