Synthetic And Natural Probes For Selective Anion Sensing
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Date
2017
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Department
Chemistry
Program
Doctor of Philosophy
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This item is made available by Morgan State University for personal, educational, and research purposes in accordance with Title 17 of the U.S. Copyright Law. Other uses may require permission from the copyright owner.
Abstract
Anions are ubiquitous in the natural world and play fundamental roles in a wide range of chemical, biological, medical, and environmental processes. Inorganic anions from both natural and different anthropogenic sources play significant role in the various disciplines of life and may often have a beneficial and/or deleterious effect to both the environment and its constituents. The obvious dichotomy between the various beneficiary uses and the adverse effects caused by the different anions definitely underscores the importance and need for robust, simple, and inexpensive techniques to monitor and determine specific anions of interest in the aforementioned. In this regard, the contributions rendered by the progresses made in the areas of anion sensor chemistry to overcome the challenges is paramount. In this dissertation work we report results for a complete synthesis and characterization of five synthetic anion sensing probes, identification of two natural anion sensing probes, and results for the investigation on selective anion sensing capabilities of these synthetic and natural probes. The five synthetic probes investigated in this dissertation work are Schiff bases derived from condensation reaction of D-(+)-Glucosamine hydrochloride with 2-hydroxy-1-naphthalehyde, salicylaldehyde, and three different substituted constituents of salicylaldehyde. The Schiff base compounds were characterized using experimental results for some physical characteristics, analytical data, and spectroscopic data. The two natural anion sensing probes were identified based on their possession of a similar or resembling binding moieties to those of the synthetic probes. Anion sensing capabilities of all the seven probes were investigated using visual (naked-eye) detection and optical spectrophotometric (UV-visible and fluorescence spectroscopy) techniques.