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Bioengineering Novel Floating Nanoparticles for Protein and Drug Delivery
Gas vesicle nanoparticles (GVNPs) are hollow protein nanoparticles produced by Halobacterium sp. NRC-1 which are being engineered for protein delivery. To advance the bioengineering potential of GVNPs, a strain of NRC-1 ...
Halobacterium Expression System for Production of Full-Length Plasmodium falciparum Circumsporozoite Protein
We recently developed a novel expression system employing the halophilic Archaeon Halobacterium sp. NRC-1 for scaled-up production and nanoparticle-display of antigenic proteins. Here, we have targeted the major human ...
Microneedle-Assisted Skin Permeation by Non-toxic Bioengineerable Gas Vesicle Nanoparticles
(American Chemical Society, 2017)
Gas vesicle nanoparticles (GVNPs) are hollow, buoyant protein organelles produced by the extremophilic microbe Halobacterium sp. NRC-1 and are being developed as bioengineerable and biocompatible antigen and drug-delivery ...