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Quantification of Variabilities of Baseflow of Watersheds
The U.S. Geological Survey National Water-Quality Assessment Project conducted a study of 225 sites in the Chesapeake Bay watershed to estimate base flow. Baseflow is the estimated volumetric discharge of water, primarily ...
Numerical Methods for Parallel Simulation of Diffusive Pollutant Transport from a Point Source
In an interdisciplinary project combining Atmospheric Physics, High Performance Computing, and Big Data, we explore a numerical method for solving a physical system modeled by a partial differential equation. The application ...
Distribution of Chemoattractants in a Heterogeneous Tissue and its Impact on Cell Cluster Migration
(2017)
Cell migration is the process in living organisms by which the body heals and diseases spread, so comprehension of this mechanism is beneficial to understanding its applications. We studied the cluster cell migration in ...
An Investigation of Small Worldness in Pancreatic Islets
(2017)
Diabetes occurs when the body’s blood sugar levels are in a state of sustained elevation. The pancreatic beta cells, organized in the islets of Langerhans, secrete a hormone called insulin that is responsible for maintaining ...
Developing the Coupling of the Mechanical to the Electrical and Calcium Systems in a Heart Cell
(2017)
As the leading cause of death in the United States, heart disease has become a principal concern in modern society. Cardiac arrhythmias can be caused by a dysregulation of calcium dynamics in cardiomyocytes. Calcium ...
Time-stepping techniques to enable the simulation of bursting behavior in a physiologically realistic computational islet
(ScienceDirect, 2015-02-14)
Physiologically realistic simulations of computational islets of beta cells require the long-time solution of several thousands of coupled ordinary differential equations (ODEs), resulting from the combination of several ...
Parallel Performance Studies for a Parabolic Test Problem on the Cluster maya
(2015)
We report parallel performance studies on each of the three uniform portions, from 2009, 2010, and 2013, of the cluster maya in the UMBC High Performance Computing Facility (HPCF) for a parabolic test problem given by a ...
Spontaneous Calcium Release in Cardiac Myocytes: Store Overload and Electrical Dynamics
(Illinois State University, 2015)
Heart disease is the leading cause of mortality in the United States. One cause of heart arrhythmia is calcium (Ca²⁺) mishandling in cardiac muscle cells. We adapt Izu's et al. mathematical reaction-diffusion model of ...
A Comparison of Solving the Poisson Equation Using Several Numerical Methods in Matlab and Octave on the Cluster maya
(2014)
Systems of linear equations resulting from partial differential equations arise frequently in many phenomena such as heat, sound, and fluid flow. We apply the finite difference method to the Poisson equation with homogeneous ...
Parallel Performance Studies for an Elliptic Test Problem on the Cluster maya
(2014)
The UMBC High Performance Computing Facility (HPCF) is the community-based, interdisciplinary core facility for scientific computing and research on parallel algorithms at UMBC. Released in Summer 2014, the current machine ...