In vitro Study of Transvascular Transport of Nanostructures using a 3D Printed Microfluidic Platform
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Date
2018-08
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Citation of Original Publication
Min Zaw, Myo & Bendler, Jordan & Ray, Arun & Lowrance, Chanda & Gu, Qimei & Daniel, Marie-Christine & Zhu, Liang & Ma, Ronghui. (2018). In vitro Study of Transvascular Transport of Nanostructures using a 3D Printed Microfluidic Platform. 10.13140/RG.2.2.10230.34887.
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This work was written as part of one of the author's official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law.
Public Domain Mark 1.0
This work was written as part of one of the author's official duties as an Employee of the United States Government and is therefore a work of the United States Government
Public Domain Mark 1.0
This work was written as part of one of the author's official duties as an Employee of the United States Government and is therefore a work of the United States Government
Abstract
Microfluidics platform simulating gold nanostructures transport in tumor vascular was fabricated using 3D printing technology. Synthesis Au nanoparticles and nanorods are used to test the fabricated device using 1µm porous membrane under 20 mmHg and 5 mmHg capillary channel pressure condition. Higher capillary channel pressure has results in higher permeate of particles and rods across membrane. Compare to spherical shape nanoparticles, nanorods structure has higher permeation. Aggregation and blockage occurred around the membrane for nanorods experiment.