Protective effects of auditory toughening on noise induced hearing loss in rats
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Type of Workapplication/pdf
viii, 87 pages
DepartmentTowson University. Department of Audiology, Speech-Language Pathology and Deaf Studies
RightsCopyright protected, all rights reserved.
There are no restrictions on access to this document. An internet release form signed by the author to display this document online is on file with Towson University Special Collections and Archives.
SubjectsDeafness, Noise induced
Noise -- Health aspects
Exposure to a sound provides protection against a subsequent traumatic sound. This toughening effect was studied in rats using different levels of stimuli. Rats were exposed to a 60 dBA or 72 dBA broad band noise for 5 days, 12 hours per day. Recovery from a 110 dB SPL 7.8 kHz pure tone presented for 20 minutes was measured using auditory brainstem response thresholds and distortion product otoacoustic emissions immediately after the traumatic exposure and 10 to 12 days later. Auditory toughening did not have an effect on hearing and outer hair cell function immediately following a traumatic sound exposure. The toughened groups showed, however, a greater recovery than the control group, which was proportionally dependent on the toughening sound intensity, 10 to 12 days after the traumatic sound exposure.