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dcterms.accessRightsThere are no restrictions on access to this document. An internet release form signed by the author to display this document online is on file with Towson University Special Collections and Archives.
dc.contributor.advisorBulmer, Mark S.
dc.contributor.authorHamilton, Casey
dc.contributor.departmentTowson University. Department of Biological Sciences
dc.date.accessioned2015-12-17T19:17:48Z
dc.date.available2015-12-17T19:17:48Z
dc.date.issued2011-10-19
dc.date.submitted2011-05
dc.description(M.S.) -- Towson University, 2011.
dc.description.abstractTermites face strong pathogenic pressures associated with their social organization and ecological attributes. Reticulitermes subterranean termites are exposed to the entomopathogenic fungus Metarhizium anisopliae, which is a natural pathogen ubiquitous in the soil that these termites nest and forage in. M. anisopliae can effectively evade insect innate immune defenses after penetrating the cuticle. Here, I describe an external antifungal defense system utilized by Reticulitermes in which salivary gland antifungal secretions with strong GNBP-associated B-1,3-glucanase activity are spread over the cuticle. Inhibition of B-1,3-glucanase activity decreases antifungal activity and increases mortality in termites exposed to a local strain of M. anisopliae. RNA interference shows that GNBP2 and termicin are essential antifungal molecules in these termites, and important components of external defenses. This external defense strategy targets fungal pathogens before cuticular penetration, and could have been important in overcoming the pathogenic pressures associated with group living and nesting in soil.
dc.formatapplication/pdf
dc.format.extentvi, 49 pages
dc.genretheses
dc.identifierdoi:10.13016/M22X3Q
dc.identifier.otherTSP2011Hamilton
dc.identifier.urihttp://hdl.handle.net/11603/1908
dc.language.isoeng
dc.relation.ispartofTowson University Archives
dc.relation.ispartofTowson University Electronic Theses and Dissertations
dc.relation.ispartofTowson University Institutional Repository
dc.rightsCopyright protected, all rights reserved.
dc.titleExternal secretions and antifungal defense in subterranean termites
dc.typeText


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