• Login
    View Item 
    •   Maryland Shared Open Access Repository Home
    • KnowledgeWorks@UBalt
    • UBalt Faculty Scholarship
    • View Item
    •   Maryland Shared Open Access Repository Home
    • KnowledgeWorks@UBalt
    • UBalt Faculty Scholarship
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Bioengineering Novel Floating Nanoparticles for Protein and Drug Delivery

    Thumbnail
    Files
    nihms-755209.pdf (465.9Kb)
    Links to Files
    http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC4856160&blobtype=pdf
    Permanent Link
    10.1016/j.matpr.2016.01.058
    http://hdl.handle.net/11603/4186
    Collections
    • UBalt Faculty Scholarship
    Metadata
    Show full item record
    Author/Creator
    Dassarma, Priya
    Karan, Ram
    Kim, Jong-Myoung
    Pecher, Wolf T
    Dassarma, Shiladitya
    Date
    2016
    Type of Work
    8 pages
    Text
    journal articles
    Citation of Original Publication
    DasSarma, P., Karan, R., Kim, J.-M., Pecher, W., & DasSarma, S. (January 01, 2016). Bioengineering Novel Floating Nanoparticles for Protein and Drug Delivery. Materials Today: Proceedings, 3, 2, 206-210.
    Subjects
    Gas vesicle nanoparticles (GVNPs)
    vaccine
    luciferase
    Gaussia princeps
    enzyme display
    Abstract
    Gas vesicle nanoparticles (GVNPs) are hollow protein nanoparticles produced by Halobacterium sp. NRC-1 which are being engineered for protein delivery. To advance the bioengineering potential of GVNPs, a strain of NRC-1 deleted for the gvpC gene (ΔgvpC) was constructed and a synthetic gene coding for Gaussia princeps luciferase was fused to an abbreviated gvpC gene on an expression plasmid. When introduced into theΔgvpC strain, an active GvpC-luciferase fusion protein bound to GVNPs resulted. These results represent both a technical improvement in the GVNP display system and its expansion for the display of active enzymes.


    Robert L. Bogomolny Library
    University of Baltimore
    1420 Maryland Ave.
    Baltimore, MD 21201
    Email: knowledgeworks@ubalt.edu


    If you wish to submit a copyright complaint or withdrawal request, please email mdsoar-help@umd.edu.

     

     

    My Account

    LoginRegister

    Browse

    This CollectionBy Issue DateTitlesAuthorsSubjectsType

    Statistics

    View Usage Statistics


    Robert L. Bogomolny Library
    University of Baltimore
    1420 Maryland Ave.
    Baltimore, MD 21201
    Email: knowledgeworks@ubalt.edu


    If you wish to submit a copyright complaint or withdrawal request, please email mdsoar-help@umd.edu.