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OVEREXPRESSION OF ADENYLATE CYCLASE ISOFORMS ALTERS CELL SIGNALING PATHWAYS IN NF1-NULL MALIGNANT PERIPHERAL NERVE SHEATH TUMORS
(2017-11)
The second messenger, cyclic-AMP (cAMP), is produced by ten adenylate cyclase (ADCY) isoforms. Previous studies indicate that ADCY isoforms may lead to either activation or inhibition of cAMP-dependent protein kinase (PKA), ...