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    Utilizing Ayurvedic literature for the identification of novel phytochemical inhibitors of botulinum neurotoxin A 

    Yalamanchili, Chinni; Manda, Vamshi K.; Chittiboyina, Amar G.; Guernieri, Rebecca L.; Harrell, William A. Jr.; Webb, Robert P.; Smith, Leonard A.; Khan, Ikhlas A. (Journal of Ethnopharmacology, 2017-02-02)
    Ethnopharmacological relevance Ayurveda, an ancient holistic system of health care practiced on the Indian subcontinent, utilizes a number of multi-plant formulations and is considered by many as a potential source for ...
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    A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A 

    Harrell, William A. Jr.; Vieira, Rebecca C.; Ensel, Susan M.; Montgomery, Vicki; Guernieri, Rebecca; Eccard, Vanessa S.; Campbell, Yvette; Roxas-Duncan, Virginia; Cardellina, John H. II; Webb, Robert P.; Smith, Leonard A. (Bioorganic & Medicinal Chemistry Letters, 2017-02-01)
    Our initial discovery of 8-hydroxyquinoline inhibitors of BoNT/A and separation/testing of enantiomers of one of the more active leads indicated considerable flexibility in the binding site. We designed a limited study to ...


    Stevenson University Library
    1525 Greenspring Valley Road
    Stevenson, MD 21153

    Website: http://stevensonlibrary.org

    Contact information:
    Elizabeth Fields
    efields2@stevenson.edu
    http://stevenson.libguides.com/sse


    If you wish to submit a copyright complaint or withdrawal request, please email mdsoar-help@umd.edu.

     

     

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    Harrell, William A. Jr. (2)
    Smith, Leonard A. (2)Webb, Robert P. (2)Campbell, Yvette (1)Cardellina, John H. II (1)Chittiboyina, Amar G. (1)Eccard, Vanessa S. (1)Ensel, Susan M. (1)Guernieri, Rebecca (1)Guernieri, Rebecca L. (1)... View MoreSubjectAcoric acid (1)Animals (1)Ayurvedic literature (1)Binding Sites (1)Bioterror agents (1)Botulinum neurotoxin serotype A inhibitors (1)Botulinum Toxins, Type A--antagonists & inhibitors (1)Botulinum Toxins, Type A--metabolism (1)Computer-aided drug discovery (1)Drug-discovery (1)... View MoreDate Issued2017 (2)Has File(s)No (2)


    Stevenson University Library
    1525 Greenspring Valley Road
    Stevenson, MD 21153

    Website: http://stevensonlibrary.org

    Contact information:
    Elizabeth Fields
    efields2@stevenson.edu
    http://stevenson.libguides.com/sse


    If you wish to submit a copyright complaint or withdrawal request, please email mdsoar-help@umd.edu.