Browsing UMBC Chemical, Biochemical & Environmental Engineering Department by Title
Now showing items 1-20 of 38
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Altered structural and mechanical properties in decellularized rabbit carotid arteries
(Elsevier B.V, 2008-12-11)Recently, major achievements in creating decellularized whole tissue scaffolds have drawn considerable attention to decellularization as a promising approach for tissue engineering. Decellularized tissues are expected ... -
Analysis of subsurface storage and streamflow generation in urban watersheds
(Wiley, 2015-01-21)Subsurface storage as a regulator of streamflow was investigated as an explanation for the large proportion of pre‐event water observed in urban streams during storm events. We used multiple lines of inquiry to explore the ... -
Biocompatible hydrogel membranes for the protection of RNA aptamer-based electrochemical sensors
(SPIE, 2013-05-31)Electrochemical-aptamer based (E-AB) sensors represent a universal specific, selective, and sensitive sensing platform for the detection of small molecule targets. Their specific detection abilities are afforded by ... -
Blood Serum Affects Polysaccharide Production and Surface Protein Expression in S. Aureus
(Juniper, 2017)Background: S. aureus biofilm serves a major role in pathogenesis. Two of the major components of bacterial biofilm are Polysaccharides intercellular adhesions (PIA) and surface proteins. It is not known how PIA and surface ... -
Bridging the divide between neuroprosthetic design, tissue engineering and neurobiology
(Frontiers Media S.A., 2010-02-08)Neuroprosthetic devices have made a major impact in the treatment of a variety of disorders such as paralysis and stroke. However, a major impediment in the advancement of this technology is the challenge of maintaining ... -
Characterization of protein release from hydrolytically degradable poly(ethylene glycol) hydrogels
(Wiley Periodicals, 2010-08-27)We present a novel fully hydrophilic, hydrolytically degradable poly(ethylene glycol) (PEG) hydrogel suitable for soft tissue engineering and delivery of protein drugs. The gels were designed to overcome drawbacks associated ... -
Design and characteristics of hydroxyapatites: effect of radiation
(Society of Photo-Optical Instrumentation Engineers (SPIE), 2018-05-14)We have prepared silicate based hard materials and have processed it with organic flux. Because of the bioactivities of hydroxyapatites with tissues, this class of materials have attracted interest for bone applications. ... -
Development of chromatofocusing techniques employing mixed-mode column packings for protein separations.
(Elsevier B.V, 2013-11-06)Recent studies reported in the literature using mixed-mode chromatography (MMC) column packings have shown that multiple modes of interactions between the column packing and proteins can be usefully exploited to yield ... -
Enhanced biochars can match activated carbon performance in sediments with high native bioavailability and low final porewater PCB concentrations
(Elsevier, 2018)A bench scale study was conducted to evaluate the effectiveness of in situ amendments to reduce the bioavailability of pollutants in sediments from a site impacted with polychlorinated biphenyls (PCBs), polycyclic aromatic ... -
Enhancement of human neural stem cell self‐renewal in 3D hypoxic culture
(Wiley Periodicals, 2016-11-21)The pathology of neurological disorders is associated with the loss of neuronal and glial cells that results in functional impairments. Human neural stem cells (hNSCs), due to their self-renewing and multipotent characteristics, ... -
Fabrication of a layered microstructured polycaprolactone construct for 3-D tissue engineering
(Taylor and Francis Online, 2012-04-02)Successful artificial tissue scaffolds support regeneration by promoting cellular organization as well as appropriate mechanical and biological functionality. We have previously shown in vitro that 2-D substrates with ... -
Fluorescence Measurement of Pericellular Oxygen
(Elsevier Inc., 2016-02-16)Under normal physiological conditions, the mitochondrial electron transport chain consumes cellular/mitochondrial oxygen (O₂) to generate a proton motive force (ΔΨm) which powers ATP synthesis. Thus, many cellular processes ... -
Fluorescent microparticles for sensing cell microenvironment oxygen levels within 3D scaffolds
(Elsevier B.V, 2009-03-14)We present the development and characterization of fluorescent oxygen-sensing microparticles designed for measuring oxygen concentration in microenvironments existing within standard cell culture and transparent three-dimensional ... -
Fluorescent silica particles for monitoring oxygen levels in three‐dimensional heterogeneous cellular structures
(Wiley Periodicals, 2012-04-17)Bacterial biofilms are a major obstacle challenging the development of more effective therapies to treat implant infections. Oxygen availability to bacterial cells has been implicated in biofilm formation and planktonic ... -
Hydrolytically degradable poly(ethylene glycol) hydrogel scaffolds as a cell delivery vehicle: Characterization of PC12 cell response
(Wiley Periodicals, 2013-06-22)The central nervous system (CNS) has a low intrinsic potential for regeneration following injury and disease, yet neural stem/progenitor cell (NPC) transplants show promise to provide a dynamic therapeutic in this complex ... -
Hydrolytically degradable poly(ethylene glycol) hydrogel scaffolds with tunable degradation and mechanical properties
(American Chemical Society, 2010-05-10)The objective of this work was to create three-dimensional (3D) hydrogel matrices with defined mechanical properties, as well as tunable degradability for use in applications involving protein delivery and cell encapsulation. ... -
Improving the recombinant human erythropoietin glycosylationusing microsome supplementation in CHO cell-free system
(Wiley, 2018)Cell-Free Protein Synthesis (CFPS) offers many advantages for the production of recombinant therapeutic proteins using the HO cell-free system. However, many complex proteins are still difficult to express using this method. ... -
Influence of cell-adhesive peptide ligands on poly(ethylene glycol) hydrogel physical, mechanical and transport properties
(Elsevier B.V, 2010-04-10)Synthetic three-dimensional (3D) scaffolds for cell and tissue engineering routinely utilize peptide ligands to provide sites for cell adhesion and to promote cellular activity. Given the fact that recent studies have ... -
Minimally invasive technique for measuring transdermal glucose with a fluorescent biosensor
(Springer Berlin Heidelberg, 2018-08-17)There is a need for blood glucose monitoring techniques that eliminate the painful and invasive nature of current methods, while maintaining the reliability and accuracy of established medical technology. This research ...