Now showing items 1-5 of 5
Multi-scale simulation of L-selectin–PSGL-1-dependent homotypic leukocyte binding and rupture
L-selectin–PSGL-1-mediated polymorphonuclear (PMN) leukocyte homotypic interactions potentiate the extent of PMN recruitment to endothelial sites of inflammation. Cell–cell adhesion is a complex phenomenon involving the ...
Cell deformation cytometry using diode-bar optical stretchers
(Society of Photo-Optical Instrumentation Engineers., 2010-08-04)
The measurement of cell elastic parameters using optical forces has great potential as a reagent-free method for cell classification, identification of phenotype, and detection of disease; however, the low throughput ...
Elastic capsule deformation in general irrotational linear flows
(IOP Publishing Ltd, 2012-07-05)
Knowledge of the response of elastic capsules to an imposed fluid flow is necessary for predicting the deformation and motion of biological cells and synthetic capsules in microfluidic devices and in microcirculation. ...
Dynamic ray tracing for modeling optical cell manipulation
Current methods for predicting stress distribution on a cell surface due to optical trapping forces are based on a traditional ray optics scheme for fixed geometries. Cells are typically modeled as solid spheres as this ...
Linear diode laser bar optical stretchers for cell deformation
(Optical Society of America, 2010-08-05)
To investigate the use of linear diode laser bars to optically stretch cells and measure their mechanical properties, we present numerical simulations using the immersed boundary method (IBM) coupled with classic ray optics. ...