Browsing UMBC Chemistry & Biochemistry Department by Issue Date
Now showing items 1-20 of 176
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Simultaneous recording of the spectral, temporal, and polarization properties of emission spectra
(SPIE, 1997-05-07)We describe a system that records simultaneously the temporal profile of both linear polarization components of all wavelengths in an emission spectrum. Our excitation source is the vacuum ultraviolet storage ring of the ... -
NIST-JANAF Thermochemical Tables. I. Ten Organic Molecules Related to Atmospheric Chemistry
(AIP, 2001-07-12)The structural, spectroscopic, and thermodynamic properties of 10 gas phase organic molecules related to atmospheric chemistry, including three peroxides and four carboxylic acids, are reviewed. The calculation of the ... -
Novel fluorescent oxygen indicator for intracellular oxygen measurements
(SPIE, 2002-07-01)Intracellular oxygen concentration is of primary importance in determining numerous physiological and pathological processes in biological systems. In this paper, we describe the application of the oxygen sensing ... -
FRET-based luminescence sensors for carbohydrates and glycoproteins analysis
(SPIE, 2004-12-07)This paper describes the development of novel particle-based fluorescence resonance energy transfer (FRET) biosensors. It describes the fundamentals of FRET in heterogeneous systems and the application of the new sensors ... -
Nanocomposite particles containing semiconductor and magnetic nanocrystals: fabrication and characterization
(SPIE, 2004-12-29)In this paper several approaches to fabricate semiconductor magnetic nanocomposite are reported. Several thiol- and amino- silane cross linked molecules were used to couple and embed CdSe and Fe3O4 nanoparticles into silica ... -
Point-of-care biosensor systems for cancer diagnostics/prognostics
(Elsevier, 2006-02-13)With the growing number of fatalities resulting from the 100 or so cancer-related diseases, new enabling tools are required to provide extensive molecular profiles of patients to guide the clinician in making viable diagnosis ... -
Effect of an Oscillating Magnetic Field on the Release Properties of Magnetic Collagen Gels
(ACS Publications, 2006-05-13)The paper describes the effect of an oscillating magnetic field (OMF) on the morphology and release properties of collagen gels containing magnetic nanoparticles and microparticles and fluorescent drug analogues. Collagen ... -
Luminescent quantum dots for cellular analysis
(SPIE, 2006-10-19)The paper describes the fabrication, characterization and applications of novel luminescent quantum dots fluorescence resonance energy transfer (FRET) based enzymatic activity probes. The luminescent probes are based on ... -
Advances in zinc sensors for studying zinc release events from pancreatic cells
(SPIE, 2006-10-25)This paper describes the fabrication and characterization of the analytical properties of fluorescence-based zinc ion sensing glass slides and antibody based zinc sensors and their application in monitoring zinc release ... -
Standoff detection using coherent backscattered spectroscopy
(SPIE, 2007-04-26)Intense laser pulses may be used for standoff detection of energetic materials. Coherent backscattered spectroscopy offers a tremendous advantage over other spectroscopic detection techniques in that it uses stimulated ... -
Chemiluminescent solid lipid nanoparticles (SLN) and interations with intact skin
(SPIE, 2009-08-24)We report the synthesis and characterization of a novel nanoparticle formulation designed for skin penetration for the purpose of skin imaging. Solid lipid nanoparticles (SLNs), a drug delivery vehicle, were used as the ... -
Quantum Dot FRET-Based Probes in Thin Films Grown in Microfluidic Channels
(ACS Publications, 2010-01-14)This paper describes the development of new fluorescence resonance energy transfer (FRET)-based quantum dot probes for proteolytic activity. The CdSe/ZnS quantum dots are incorporated into a thin polymeric film, which is ... -
Gold Nanoparticle−Quantum Dot−Polystyrene Microspheres as Fluorescence Resonance Energy Transfer Probes for Bioassays
(ACS Publications, 2011-01-31)The paper describes the development of highly sensitive particle-based fluorescence resonance energy transfer (FRET) probes that do not use molecular fluorophores as donors and acceptors. In these probes, CdSe/ZnS luminescent ... -
Thumb inhibitor binding eliminates functionally important dynamics in the hepatitis C virus RNA polymerase
(Wiley, 2012-07-31)Hepatitis C virus (HCV) has infected almost 200 million people worldwide, typically causing chronic liver damage and severe complications such as liver failure. Currently, there are few approved treatments for viral ... -
Identifying Nonlinear Correlations in High Dimensional Data with Application to Protein Molecular Dynamics Simulations
(2013)Complex biomolecules such as proteins can respond to changes in their environment through a process called allostery, which plays an important role in regulating the function of these biomolecules. Allostery occurs when ... -
Block Cyclic Distribution of Data in pbdR and its Effects on Computational Efficiency
(2013)Programming with big data in R (pbdR), a package used to implement high-performance computing in the statistical software R, uses block cyclic distribution to organize large data across many processes. Because computations ... -
Soluble guanylate cyclase crystal clear: 1st crystal structure of the wild-type human heterodimeric sGC catalytic domains and implications for activity
(Springer, 2013-08-29)Soluble guanylate cyclase (sGC) is the key enzyme in the NO-sGC-cGMP signaling cascade crucial in regulating the cardiovascular system. Low output of this system causes hypertension and acute heart failure, which are the ... -
Nonlinear Measures of Correlation and Dimensionality Reduction with Application to Protein Motion
(2014)The study of allostery, a regulatory process that occurs in complex macromolecules such as proteins, is of particular interest as it has a key role in determining the function of these macromolecules. Allostery produces ... -
Merging Metabolism and Power: Development of a Novel Photobioelectric Device Driven by Photosynthesis and Respiration
(PLOS, 2014-01-22)Generation of renewable energy is one of the grand challenges facing our society. We present a new bio-electric technology driven by chemical gradients generated by photosynthesis and respiration. The system does not require ...