Now showing items 74-93 of 232

    • Identifying Nonlinear Correlations in High Dimensional Data with Application to Protein Molecular Dynamics Simulations 

      Bailey, William J.; Chambless, Claire A.; Cho, Brandynne M.; Smith, Jesse D.; Raim, Andrew M.; Adragni, Kofi P.; Thorpe, Ian F. (2013)
      Complex biomolecules such as proteins can respond to changes in their environment through a process called allostery, which plays an important role in regulating the function of these biomolecules. Allostery occurs when ...
    • IDL: A Possible Alternative to Matlab 

      Coman, Ecaterina (2012)
      Created by Exelis Visual Information Solutions, IDL (Interactive Data Language) is a commercial package used for data analysis. We compared the usability and efficiency of IDL to that of Matlab to determine if IDL is a ...
    • Impact of Calcium Store Overload and Electrical Dynamics on Cardiac Myocytes 

      Alexander, Amanda M.; DeNardo, Erin K.; Frazier III, Eric; McCauley, Michael; Rojina, Nicholas; Coulibaly, Zana; Peercy, Bradford E.; Izu, Leighton T. (2015)
      The heart's main function of pumping blood to the body is a complicated process separated into two major steps. Initially, the heart is relaxed and blood flows freely into the ventricles and atria from the veins, then the ...
    • An Implementation of Binomial Method of Option Pricing using Parallel Computing 

      Popuri, Sai K.; Raim, Andrew M.; Neerchal, Nagaraj K.; Gobbert, Matthias K.
      The Binomial method of option pricing is based on iterating over discounted option payoffs in a recursive fashion to calculate the present value of an option. Implementing the Binomial method to exploit the resources of a ...
    • Improvements to the Deep Learning Classification of Compton Camera Based Prompt Gamma Imaging for Proton Radiotherapy 

      Basalyga, Jonathan N.; Barajas, Carlos A.; Kroiz, Gerson C.; Gobbert, Matthias K.; Maggi, Paul; Polf, Jerimy (2020-05)
      Real-time imaging has potential to greatly increase the effectiveness of proton beam therapy for cancer treatment. One promising method of real-time imaging is the use of a Compton camera to detect prompt gamma rays, which ...
    • Improving the Computational Effciency of Downscaling GCM data for Use in SWAT 

      Evans, Christopher; Gartrell, Abigail; Gomez, Lauren; Mouyebe, Moise; Oxley, Darius; Popuri, Sai Kumar; Neerchal, Nagaraj K.; Mehta, Amita (2014)
      This project creates software tools to streamline the computational procedures to generate high-resolution weather parameters from low resolution Global Climate Models (GCM) to be input into the Soil and Water Assessment ...
    • Incorporating age and delay into models for biophysical systems 

      KhudaBukhsh, Wasiur R.; Kang, Hye-Won; Kenah, Eben; Rempala, Grzegorz A.
      In many biological systems, chemical reactions or changes in a physical state are assumed to occur instantaneously. For describing the dynamics of those systems, Markov models that require exponentially distributed inter-event ...
    • Individual and community-level risk for COVID-19 mortality in the United States 

      Jin, Jin; Agarwala, Neha; Kundu, Prosenjit; Harvey, Benjamin; Zhang, Yuqi; Wallace, Eliza; Chatterjee, Nilanjan (Nature, 2020-12-11)
      Reducing COVID-19 burden for populations will require equitable and effective risk-based allocations of scarce preventive resources, including vaccinations. To aid in this effort, we developed a general population risk ...
    • Inexact Methods for Symmetric Stochastic Eigenvalue Problems 

      Lee, Kookjin; Sousedík, Bedřich (2018-11-02)
      We study two inexact methods for solutions of random eigenvalue problems in the context of spectral stochastic finite elements. In particular, given a parameter-dependent, symmetric matrix operator, the methods solve for ...
    • The Influence of Stochastic Parameters on Calcium Waves in a Heart Cell 

      Brewster, Matthew W. (2013)
      Calcium is a critical component in many cellular functions. It serves many important functions such as signal transduction, contraction of muscles, enzyme function, and maintaining potential difference across excitable ...
    • Informational Requirements for Transcriptional Regulation 

      O'Neill, Patrick K.; Forder, Robert; Erill, Ivan (2014-05-01)
      Transcription factors (TFs) regulate transcription by binding to specific sites in promoter regions. Information theory provides a useful mathematical framework to analyze the binding motifs associated with TFs but imposes ...
    • Informational Requirements for Transcriptional Regulation 

      O'Neill, Patrick K.; Forder, Robert; Erill, Ivan (Mary Ann Liebert, 2014-05-01)
      Transcription factors (TFs) regulate transcription by binding to specific sites in promoter regions. Information theory provides a useful mathematical framework to analyze the binding motifs associated with TFs but imposes ...
    • Intel Concurrent Collections as a Method for Parallel Programming 

      Adjogah, Richard; Mckissack, Randal; Sibeudu, Ekene; Raim, Andrew M.; Gobbert, Matthias K.; Craymer, Loring (2011)
      Computer hardware has become parallel in order to run faster and more efficient. One of the current standard parallel coding libraries is MPI (Message Passing Interface). The Intel Corporation is developing a new parallel ...
    • The Interaction of Calcium and Metabolic Oscillations in Pancreatic β-cells 

      Aronne, Mary; Clapp, Samantha; Jung, Soohwan; Kramer, Abigail; Wang, William; Patwardhan, Janita; Peercy, Bradford E.; Sherman, Arthur (Illinois State University, 2017)
      Diabetes is a disease characterized by an excessive level of glucose in the bloodstream, which may be a result of improper insulin secretion. Insulin is secreted in a bursting behavior of pancreatic β -cells in islets, ...
    • The Interaction of Calcium and Metabolic Oscillations in Pancreatic β-cells 

      Aronne, Mary; Clapp, Samantha; Jung, Soohwan; Kramer, Abigail; Wang, William; Patwardhan, Janita; Peercy, Bradford E.; Sherman, Arthur (2016)
      Diabetes is a disease characterized by an excessive level of glucose in the blood-stream, which may be a result of improper insulin secretion. Insulin is secreted in a bursting behavior of pancreatic β-cells in the islets ...
    • Interval Estimation of the Overlapping Coefficient of Two Exponential Distributions 

      Jose, Sibil; Thomas, Seemon; Mathew, Thomas (Atlantis Press SARL, 2019-04-22)
      For the overlapping coefficient between two one-parameter or two-parameter exponential distributions, confidence intervals are developed using generalized pivotal quantities. The accuracy of the proposed solutions are ...
    • Investigating Oscillation Loss in Computational Islets 

      Gearhart, Gemma; Jiang, Shuai; May, Thomas J.; Pan, Jane; Khuvis, Samuel; Gobbert, Matthias K.; Peercy, Bradford E.; Sherman, Arthur (2013)
      The study of pancreatic β -cells comprises a crucial part of the study of the group of diseases known as diabetes. These cells exist in groups known as islets of Langerhans and are responsible for storing and producing ...
    • Investigating the Use of pMatlab to Solve the Poisson Equation on the Cluster maya 

      Swatski, Sarah (2014)
      Many physical phenomena can be described by partial differential equations which can be discretized to form systems of linear equations. We apply the finite difference method to the Poisson equation with homogeneous ...
    • An Investigation of Small Worldness in Pancreatic Islets 

      Falgout, Elise; Frett, Destiny; Neil, Lorenzo; Schumm, Ryan; Patwardhan, Janita; Peercy, Brad; Sherman, Arthur (2017)
      Diabetes occurs when the body’s blood sugar levels are in a state of sustained elevation. The pancreatic beta cells, organized in the islets of Langerhans, secrete a hormone called insulin that is responsible for maintaining ...