The nucleotide sequence of the Escherichia coli fus gene, coding for elongation factor G.

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dc.contributor.authorZengel, Janice M.
dc.contributor.authorArcher, Richard H.
dc.contributor.authorLindahl, Lasse
dc.date.accessioned2019-06-04T19:32:53Z
dc.date.available2019-06-04T19:32:53Z
dc.date.issued1984-02-24
dc.description.abstractWe have determined the nucleotide sequence of the Escherichia coli fus gene, which codes for elongation factor G. The protein product of the sequenced gene contains 703 amino acids, with a predicted molecular weight of 77,444. The fus gene shows the nonrandom pattern of codon usage typical of ribosomal proteins and other proteins synthesized at a high level. We have identified several potential promoter sequences within the gene. One of these sequences may correspond to the secondary promoter for expression of the downstream tufA gene (encoding elongation factor Tu) whose activity has been described previously (1,2). A comparison of the nucleotide and amino acid sequences of elongation factors G and Tu reveals a limited but significant homology between the two proteins within the 150 amino acid residues at their amino-terminal ends.en_US
dc.description.sponsorshipThis work was supported by Public Health Service grant AI 15286 from the National Institute of Allergy and Infectious Diseases.en_US
dc.description.urihttps://www.ncbi.nlm.nih.gov/pubmed/6322136en_US
dc.format.extent12 pagesen_US
dc.genrejournal articlesen_US
dc.identifierdoi:10.13016/m2ksmv-hs9e
dc.identifier.citationJanice M. Zengel Richard H. Archer Lasse Lindahl, The nucleotide sequence of the Escherichta coli fus gene, coding for elongation factor G, Nucleic Acids Research, Volume 12, Issue 4, 24 February 1984, Pages 2181–2192, https://doi.org/10.1093/nar/12.4.2181en_US
dc.identifier.urihttps://doi.org/10.1093/nar/12.4.2181
dc.identifier.urihttp://hdl.handle.net/11603/14013
dc.language.isoen_USen_US
dc.publisherOxford University Pressen_US
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Biological Sciences Department Collection
dc.relation.ispartofUMBC Faculty Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.subjectEscherichia coli fus geneen_US
dc.subjectelongation factors G and Tuen_US
dc.subjectribosomal proteinsen_US
dc.titleThe nucleotide sequence of the Escherichia coli fus gene, coding for elongation factor G.en_US
dc.typeTexten_US

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