Gu, YangXu, Peng2020-11-172020-11-172020-10-28Gu, Yang; Xu, Peng; Synthetic yeast brews neuroactive compounds; Nature Chemical Biology (2020); https://www.nature.com/articles/s41589-020-00691-5https://doi.org/10.1038/s41589-020-00691-5http://hdl.handle.net/11603/20078Metabolic engineering offers the flexibility to meet market demand for bioactive natural products but can be hampered when a necessary protein or intermediate is toxic. In yeast, modifying the subcellular localization of biosynthetic enzymes can alleviate toxicity and increase production titer.2 pagesen-USThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.metabolic engineeringbioactive natural productsyeastbiosynthetic enzymesText