Lindahl, LasseRahman, NusratRahman, Nusrat2019-10-112019-10-112017-01-0111736http://hdl.handle.net/11603/15039Ribosome biogenesis is a highly regulated high-energy requiring process; it is coordinated with cell cycle and proliferation. Defects in ribosome assembly are connected with abnormal growth-related diseases. Ribosomal protein L5 is reported to involve regulating level of tumor-suppressor protein p53 in metazoans. Although the presence of extra-ribosomal L5 is reported in multiple organisms, systematic characterization of its fate in ribosome biogenesis stresses remains to be explored. Here we checked the fate of L5 in various nucleolar/ribosome stresses and commented on possible source of the accumulation. The variation in L5 accumulation may provide further understanding of different cell surveillance mechanisms.This item may be protected under Title 17 of the U.S. Copyright Law. It is made available by UMBC for non-commercial research and education. For permission to publish or reproduce, please see http://aok.lib.umbc.edu/specoll/repro.php or contact Special Collections at speccoll(at)umbc.edup53-freep53-independentRibosomal protein L5Ribosome biogenesisText