Chipriano, Elizabeth N.2023-11-282023-11-282015-08http://hdl.handle.net/11603/30872This project aims to determine the number of virus particles transmitted to non-human primates after intra-rectal challenge. The virus, SIVmac239X, is a transfection derived stock containing ten molecularly tagged variants which are functionally equivalent but genetically distinct. Challenge stocks will be created following exposure to virus-free exosomes isolated from various infected cell types including monocyte derived macrophages which are a primary target of SIV.35 pagesen-USText