Rouhakhtar, Pamela RakhshanPitts, Steven C.Millman, Zachary B.Andorko, Nicole D.Redman, SamanthaWilson, CamilleDemro, CarolinePhalen, Peter L.Walsh, BarbaraWoods, ScottReeves, Gloria M.Schiffman, Jason2019-03-152019-03-152019-04P.J. Rakhshan Rouhakhtar , Steven C. Pitts , Zachary B. Millman ,et.al, The impact of age on the validity of psychosis-risk screening in a sample of help-seeking youth, Psychiatry Research Volume 274, April 2019, Pages 30-35, https://doi.org/10.1016/j.psychres.2019.02.020https://doi.org/10.1016/j.psychres.2019.02.020http://hdl.handle.net/11603/13072Self-report screening instruments offer promise in furthering early identification of at-risk youth, yet current efforts are limited by false positive rates. Identifying moderators of accuracy is a potential step towards improving identification and prevention efforts. We investigated the moderating effect of age on self-reported attenuated positive symptoms from the Prime Screen and clinician diagnosed clinical high-risk/early psychosis (CHR/EP) status. Participants (N = 134) were racially diverse, lower-income, help-seeking adolescents and young adults from a primarily urban community. The overall model predicting CHR/EP status was significant, with results suggesting the presence of a trending interaction between age and Prime Screen symptoms. Analyses indicated that number of items endorsed to predict CHR/EP decreased with age (youngest group [M = 12.99] cut off = 6 items; middle age group [M = 14.97] cut off = 3; oldest age group [M = 18.40] cut off = 1). Although younger participants endorsed more risk items on average, follow up analyses suggested that the Prime Screen was a more accurate predictor of clinician-diagnosed-risk among older participants relative to their younger peers. The current study builds on the literature identifying moderators of psychosis-risk screening measure accuracy, highlighting potential limitations of CHR/EP screening tools in younger populations.6 pagesen-USThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.Attribution-NonCommercial-NoDerivs 3.0 United Stateshttp://creativecommons.org/licenses/by-nc-nd/3.0/us/Prime Screen and clinician diagnosed clinical high-risk/early psychosis (CHR/EP)psychosis-risk syndromesstructured interview for psychosis-risk syndromes (SIPS)prime screen scoringText