Browsing by Author "O'Brien, Peggy L."
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Item Family member opioid prescriptions and opioid use disorder(Elsevier, 2019-02-28) Ali, Mir M.; Henke, Rachel Mosher; Mutter, Ryan; O'Brien, Peggy L.; Cutler, Eli; Mazer-Amirshahi, Maryann; Pines, Jesse M.It is recognized that family members are a major source of diverted opioids. Yet it is not known how family member opioid prescriptions predict the development of an opioid use disorder (OUD).We conducted an observational study using commercial health care claims to investigate the association between a family member opioid prescription and an individual having an OUD-related claim in a large sample of patients with commercial insurance. We found that individuals had higher odds of having an OUD when a family member had an opioid prescription. This effect was magnified in spouses and employees compared with adolescents and young adult dependents. In addition, adult dependents with a pre-existing non-OUD substance use disorder had higher odds of having an OUD when a family member also had an opioid prescription. Given the high risk of opioid-related morbidity and mortality, more attention should be given to safeguard opioid diversion and to facilitate appropriate disposal of unused opioids.Item Opioid Prescribing to Adolescents in the United States From 2005 to 2016(American Psychiatric Association, 2018-07-09) Henke, Rachel Mosher; Tehrani, Ali Bonakdar; Ali, Mir M.; Mutter, Ryan; Mazer-Amirshahi, Maryann; O'Brien, Peggy L.; Mark, Tami L.Objective: This study assessed trends in days’ supply for opioid prescriptions filled by adolescents with commercial insurance and Medicaid. Methods: IBM MarketScan commercial and Medicaid pharmacy claims data were used to measure days’ supply among adolescents (2005–2016) and to determine whether there were differences between patients with commercial insurance or Medicaid coverage. Results: The 2–3 days’ supply decreased from 50.5% (2005) to 36.7% of fills (2016), while 4–5 days’ supply increased from 30.2% to 37.7%. Fills of 6–7 and 8–15 days increased slightly. Fills of over 30 days remained near 0.0%, and one-day fills remained at 1.0–2.0% until 2016, when they increased to 3.6% Conclusions: For adolescents, fills of prescription opioids generally exceeded three days. Efforts to reduce opioid prescribing through guidelines, prescription drug monitoring programs, and limits on days’ supply do not appear to have affected prescribing for adolescents as much as desired.