UMBC Department of Marine Biotechnology
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The Department of Marine Biotechnology (DMB) is partner member of the Institute of Marine and Environmental Technology (IMET), a joint University System of Maryland research institute capitalizing on the strengths of the University of Maryland, Baltimore County, the University of Maryland Center for Environmental Sciences, and the University of Maryland, Baltimore. DMB is premier research center for basic and translational research in marine biotechnology and molecular microbiology. Researchers use the tools of modern molecular biology and biotechnology to make basic scientific discoveries that may be applied to study, protect and enhance marine and estuarine resources. DMB faculty focus on key areas of marine molecular biology to solve practical problems confronting the Chesapeake Bay and the greater marine ecosystem and to develop new technologies for translational application and economic advancement. DMB provides an exceptional environment for specialized training and mentoring of tomorrow’s biotechnology workforce.
The department is based at the Columbus Center in downtown Baltimore. Faculty have access to extensive research facilities, including an 18,000 square-foot, fully-contained, recirculating marine aquaculture facility, a versatile high-volume fermentation facility, and a wide assortment of advanced biomolecular instrumentation.
Recent Submissions
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Cross-Hemispheric Genetic Diversity and Spatial Genetic Structure of Callinectes sapidus Reovirus 1 (CsRV1)
(MDPI, 2023-02-18)The movement of viruses in aquatic systems is rarely studied over large geographic scales. Oceanic currents, host migration, latitude-based variation in climate, and resulting changes in host life history are all potential ... -
"What is the Shape of Water" with CIRCA-IMET Artist-in-Residence
(IMET, 2019-06-26) -
Pacific oysters are a sink and a potential source of the eelgrass pathogen, Labyrinthula zosterae
(Inter-Research, 2022-12-15)Oyster aquaculture and seagrasses often co-occur and are each vital to the ecological and economic value of coastal ecosystems. Global declines in seagrasses, including Zostera mari - na, have recently been observed in ... -
Seasonal trends of PCBs in air over Washington DC reveal localized urban sources and the influence of Anacostia River
(Elsevier, 2022-10-27)Semi-volatile organic compounds like polychlorinated biphenyls (PCBs) undergo diffusive exchange flux between a water body and the overlying air. The magnitude of this exchange can be a substantial component of the ... -
Genetic compensation of triacylglycerol biosynthesis in the green microalga Chlamydomonas reinhardtii
(Wiley, 2022-06-21)Genetic compensation has been proposed to explain phenotypic differences between gene knockouts and knockdowns in several metazoan and plant model systems. With the rapid development of reverse genetic tools such as ... -
Reproductive sterility in aquaculture: A review of induction methods and an emerging approach with application to Pacific Northwest finfish species
(Wiley, 2022-07-20)Aquaculture is the fastest-growing food-production sector and is striving to become a long-term sustainable approach to meet the rising global demand for seafood. During the expansion and advancement of aquaculture, ... -
Intranasal vaccination of hamsters with a Newcastle disease virus vector expressing the S1 subunit protects animals against SARS-CoV-2 disease
(Nature, 2022-06-20)The coronavirus disease-19 (COVID-19) pandemic has already claimed millions of lives and remains one of the major catastrophes in the recorded history. While mitigation and control strategies provide short term solutions, ... -
Genetic subtyping and phylogenetic analysis of HA and NA from avian influenza virus in wild birds from Peru reveals unique features among circulating strains in America
(PLOS, 2022-06-07)Avian influenza virus (AIV) represents a major concern with productive implications in poultry systems but it is also a zoonotic agent that possesses an intrinsic pandemic risk. AIV is an enveloped, negative-sense and ... -
Chemogenetic Depletion of Hypophysiotropic GnRH Neurons Does Not Affect Fertility in Mature Female Zebrafish
(MDPI, 2022-05-17)The hypophysiotropic gonadotropin-releasing hormone (GnRH) and its neurons are crucial for vertebrate reproduction, primarily in regulating luteinizing hormone (LH) secretion and ovulation. However, in zebrafish, which ... -
Current advances in molecular, biochemical, and computational modeling analysis of microalgal triacylglycerol biosynthesis
(Elsevier, 2016-07-14)Triacylglycerols (TAGs) are highly reduced energy storage molecules ideal for biodiesel production. Microalgal TAG biosynthesis has been studied extensively in recent years, both at the molecular level and systems level ... -
Advantages, Factors, Obstacles, Potential Solutions, and Recent Advances of Fish Germ Cell Transplantation for Aquaculture—A Practical Review
(MDPI, 2022-02-10)Germ cell transplantation technology enables surrogate offspring production in fish. This technology has been expected to mitigate reproductive barriers, such as long generation time, limited fecundity, and complex broodstock ... -
UNDER THE BAY: An Augmented Reality Project
(2021)“Under the Bay” tells the story of a world beneath the surface of the Chesapeake Bay and really all estuaries and oceans. In this augmented reality project a user can point their cell phone at the water — or anywhere in ... -
Vasoactive intestinal peptide indirectly elicits pituitary LH secretion independent of GnRH in female zebrafish
(Oxford University Press, 2022-01-03)Vasoactive intestinal peptide (Vip) regulates luteinizing hormone (LH) release through the direct regulation of gonadotropin-releasing hormone (GnRH) neurons at the level of the brain in female rodents. However, little ... -
Newcastle Disease Virus Vectored Chicken Infectious Anaemia Vaccine Induces Robust Immune Response in Chickens
(MDPI, 2021-10-02)Newcastle disease virus (NDV) strain R2B, with an altered fusion protein cleavage site, was used as a viral vector to deliver the immunogenic genes VP2 and VP1 of chicken infectious anaemia virus (CIAV) to generate a ... -
First data on aquaculture of the Tripletail, Lobotes surinamensis, a promising candidate species for U.S. marine aquaculture
(Wiley Online Library, 2021-05-18)The Tripletail, Lobotes surinamensis, is a warm-water pelagic fish that is increasingly targeted by U.S. anglers. The superior quality of Tripletail flesh coupled with the lack of domestic commercial fisheries stimulated ... -
Whole transcriptome analysis reveals changes in expression of immune-related genes during and after bleaching in a reef-building coral
(The Royal Society, 2015-04-01)Climate change is negatively affecting the stability of natural ecosystems, especially coral reefs. The dissociation of the symbiosis between reef-building corals and their algal symbiont, or coral bleaching, has been ... -
Isolation, Identification, and Genomic Analysis of a Novel Reovirus from Healthy Grass Carp and Its Dynamic Proliferation In Vitro and In Vivo
(MDPI, 2021-04-16)A new grass carp reovirus (GCRV), healthy grass carp reovirus (HGCRV), was isolated from grass carp in 2019. Its complete genome sequence was determined and contained 11 dsRNAs with a total size of 23,688 bp and 57.2 mol% ... -
Bacterial community analysis of marine recirculating aquaculture system bioreactors for complete nitrogen removal established from a commercial inoculum
(Elsevier, 2019-03-30)An experimental recirculating aquaculture system was constructed under ambient seawater conditions to compare microbial community diversity of nitrifying and denitrifying biofilters that were derived from a commercial ... -
Gnrh2 maintains reproduction in fasting zebrafish through dynamic neuronal projection changes and regulation of gonadotropin synthesis, oogenesis, and reproductive behaviors
(Springer Nature, 2021-03-23)Restricted food intake, either from lack of food sources or endogenous fasting, during reproductive periods is a widespread phenomenon across the animal kingdom. Considering previous studies show the canonical upstream ... -
Effects of Infectious Diseases on Population Dynamics of Marine Organisms in Chesapeake Bay
(Springer Nature, 2021-03-24)Diseases are important drivers of population and ecosystem dynamics. This review synthesizes the effects of infectious diseases on the population dynamics of nine species of marine organisms in the Chesapeake Bay. Diseases ...