The Hilltop Institute works to advance the health and wellbeing of people and communities through research and analysis. The Hilltop Institute strives to be a pre-eminent resource for federal, state, and local policymakers, and to contribute to the broad understanding of how better to serve people and communities. The Hilltop Institute was previously the Center for Health Program Development and Management--it changed it's name to The Hilltop Institute in 2008.

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Recent Submissions

  • Predicting Hospital Readmissions in a Commercially Insured Population over Varying Time Horizons 

    Henderson, Morgan; Hirshon, Jon Mark; Han, Fei; Donohue, Megan; Stockwell, Ian (Springer, 2022-11-28)
    Background -- Reducing hospital readmissions is a federal policy priority, and predictive models of hospital readmissions have proliferated in recent years; however, most such models tend to focus on the 30-day readmission ...
  • The Natural History of Hepatitis C Virus Infection: Host, Viral, and Environmental Factors 

    Thomas, David L.; Astemborski, Jacquie; Rai, Rudra M.; Anania, Frank A.; Schaeffer, Melody; Galai, Noya; Nolt, Karen; Nelson, Kenrad E.; Strathdee, Steffanie A.; Johnson, Lisette; Laeyendecker, Oliver; Boitnott, John; Wilson, Lucy E.; Vlahov, David (AMA, 2000-07-26)
    Context Hepatitis C virus (HCV) infection may resolve (viral clearance), persist without complications, or cause end-stage liver disease (ESLD). The frequency and determinants of these outcomes are poorly understood. Objective ...
  • HTLV-II and Bacterial Infections Among Injection Drug Users 

    Safaeian, Mahboobeh; Wilson, Lucy E.; Taylor, Ellen; Thomas, David L.; Vlahov, David (Wolters Kluwer, 2000-06-09)
    Objective: To examine whether select bacterial infections are associated with HTLV-II infection among injection drug users, we conducted a nested case control study within an ongoing cohort study. Method: HTLV-II ...
  • Dynamics of SEN Virus Infection among Injection Drug Users 

    Wilson, Lucy E.; Umemura, Takeji; Astemborski, Jacquie; Ray, Stuart C.; Alter, Harvey J.; Strathdee, Steffanie A.; Vlahov, David; Thomas, David L. (Oxford University Press, 2001-11-15)
    SEN virus (SENV) is a recently discovered group of DNA viruses whose members (SENV-D and SENV-H) are linked to posttransfusion hepatitis. Of 397 injection drug users (IDUs) in Baltimore, Maryland, SENV-D infection was ...
  • Prospective study of infective endocarditis among injection drug users 

    Wilson, Lucy E.; Thomas, David L.; Astemborski, Jacqueline; Freedman, Terri L.; Vlahov, David (Oxford University Press, 2002-06-15)
    To determine the effect of human immunodeficiency virus (HIV) infection and other factors on infective endocarditis (IE) among injection drug users (IDUs), the incidence of IE was determined according to HIV status in a ...
  • Progression of liver fibrosis among injection drug users with chronic hepatitis C 

    Wilson, Lucy E.; Torbenson, Michael; Astemborski, Jacquie; Faruki, Hawazin; Spoler, Charles; Rai, Rudra; Mehta, Shruti; Kirk, Gregory D.; Nelson, Kenrad; Afdhal, Nezam; Thomas, David L. (Wiley, 2006-03-23)
    Although most hepatitis C virus (HCV) infections are acquired by injection drug use, prospective data on the progression of liver fibrosis are sparse. Baseline liver biopsies were obtained (1996–1998) on a random sample ...
  • Incidence of, Risk Factors for, Clinical Presentation, and 1-Year Outcomes of Infective Endocarditis in an Urban HIV Cohort 

    Gebo, Kelly A; Burkey, Matthew D; Lucas, Gregory M; Moore, Richard D; Wilson, Lucy (Wolters Kluwer, 2006-08-25)
    Background: Previous studies described infective endocarditis (IE) in the era before highly active antiretroviral therapy (HAART); however, IE has not been well studied in the current HAART era. We evaluated the incidence ...
  • The incidence of and risk factors for MRSA bacteraemia in an HIV-infected cohort in the HAART era 

    Burkey, MD; Wilson, LE; Moore, RD; Lucas, GM; Francis, J; Gebo, KA (Wiley, 2008-10-27)
    Objectives To define the incidence and risk factors for methicillin resistant Staphylococcus aureus (MRSA) bacteraemia in an HIV-infected population. Methods From January 1, 2000 to December 31, 2004, we conducted a ...
  • Effect of age and HAART regimen on clinical response in an urban cohort of HIV-infected individuals 

    Greenbaum, Adena H; Wilson, Lucy E; Keruly, Jeanne C; Moore, Richard D; Gebo, Kelly A (Wolters Kluwer, 2008-08-03)
    Objectives: The prevalence of HIV infection in older patients (≥50 years) is increasing due to HAART, and new HIV infections in older patients. Some earlier studies suggest that older patients respond differently to HAART ...
  • The Management of Treatment-Experienced HIV-Infected Patients: New Drugs and Drug Combinations 

    Wilson, Lucy E.; Gallant, Joel E.; Mayer, Kenneth H. (Oxford University Press, 2009-01-15)
    The recent availability of new antiretroviral agents for the treatment of human immunodeficiency virus (HIV) infection has increased treatment options and has improved the durability, tolerability, and long-term efficacy ...
  • HIV-related medical service use by rural/urban residents: a multistate perspective 

    Wilson, Lucy E.; Korthuis, P. Todd; Fleishman, John A.; Conviser, Richard; Lawrence, Perrin B.; Moore, Richard D; Gebo, Kelly A. (Taylor & Francis, 2011-03-10)
    Objective: Geographic location may be related to the receipt of quality HIV health care services. Clinical outcomes and health care utilization were evaluated in rural, urban, and peri-urban patients seen at high-volume ...
  • Incidence of and risk factors for bacteraemia in HIV-infected adults in the era of highly active antiretroviral therapy 

    Yehia, BR; Fleishman, JA; Wilson, L; Hicks, PL; Gborkorquellie, TT; Gebo, KA (Wiley, 2011-03-23)
    Background HIV-infected patients have an increased risk for bacteraemia compared with HIV-negative patients. Few data exist on the incidence of and risk factors for bacteraemia across time in the current era of highly ...
  • First NDM-Positive Salmonella sp. Strain Identified in the United States 

    Savard, Patrice; Gopinath, Ramya; Zhu, Wenming; Kitchel, Brandon; Rasheed, J. Kamile; Tekle, Tsigereda; Roberts, Ava; Ross, Tracy; Razeq, Jafar; Landrum, B. Mark; Wilson, Lucy E.; Limbago, Brandi; Perl, Trish M.; Carroll, Karen C. (American Society for Microbiology, 2011-11-11)
  • Assessing the Burden of Acinetobacter baumannii in Maryland: A Statewide Cross-Sectional Period Prevalence Survey 

    Thorn, Kerri A.; Maragakis, Lisa L.; Richards, Katie; Johnson, J. Kristie; Roup, Brenda; Lawson, Patricia; Harris, Anthony D.; Fuss, Elizabeth P.; Pass, Margaret A.; Blythe, David; Perencevich, Eli N.; Wilson, Lucy; Maryland MDRO Prevention Collaborative (Cambridge University Press, 2015-01-02)
    Objective. To determine the prevalence of Acinetobacter baumannii, an important healthcare-associated pathogen, among mechanically ventilated patients in Maryland. Design. The Maryland MDRO Prevention Collaborative ...
  • Evaluating the Accuracy of Sampling to Estimate Central Line–Days Simplification of the National Healthcare Safety Network Surveillance Methods 

    Thompson, Nicola D.; Edwards, Jonathan R.; Bamberg, Wendy; Beldavs, Zintars G.; Dumyati, Ghinwa; Godine, Deborah; Maloney, Meghan; Kainer, Marion; Ray, Susan; Thompson, Deborah; Wilson, Lucy; Magill, Shelley S. (Cambridge University Press, 2015-01-02)
    OBJECTIVE. To evaluate the accuracy of weekly sampling of central line-associated bloodstream infection (CLABSI) denominator data to estimate central line-days (CLDs). DESIGN. Obtained CLABSI denominator logs showing ...
  • Outbreak of Hepatitis C Virus Infections At an Outpatient Hemodialysis Facility: The Importance of Infection Control Competencies 

    Rao, Agam K.; Luckman, Emily; Wise, Matthew E.; MacCannell, Taranisia; Blythe, David; Lin, Yulin; Xia, Guoliang; Drobeniuc, Jan; Noble-Wang, Judith; Arduino, Matthew J.; Thompson, Nicola D.; Patel, Priti R.; Wilson, Lucy E. (American Nephrology Nurses Association, 2015-11-18)
    In the United States, the prevalence of hepatitis C virus infection among patients treated in hemodialysis facilities is five times higher than among the general population. This study investigated eight new hepatitis C ...
  • Epidemiology of Community-Associated Clostridium difficile Infection, 2009 Through 2011 

    Chitnis, Amit S.; Holzbauer, Stacy M.; Belflower, Ruth M.; Winston, Lisa G.; Bamberg, Wendy M.; Lyons, Carol; Farley, Monica M.; Dumyati, Ghinwa K.; Wilson, Lucy E.; Beldavs, Zintars G.; Dunn, John R.; Gould, L. Hannah; MacCannell, Duncan R.; Gerding, Dale N.; McDonald, L. Clifford; Lessa, Fernanda C. (AMA, 2013-07-22)
    Importance Clostridium difficile infection (CDI) has been increasingly reported among healthy individuals in the community. Recent data suggest that community-associated CDI represents one-third of all C difficile cases. ...
  • Effect of Nucleic Acid Amplification Testing on Population-Based Incidence Rates of Clostridium difficile Infection 

    Gould, Carolyn V.; Edwards, Jonathan R.; Cohen, Jessica; Bamberg, Wendy M.; Clark, Leigh Ann; Farley, Monica M.; Johnston, Helen; Nadle, Joelle; Winston, Lisa; Gerding, Dale N.; McDonald, L. Clifford; Lessa, Fernanda C.; Beldavs, Zintars; Hanna, Samir; Hollick, Gary; Holzbauer, Stacy; Lyons, Carol; Phipps, Erin; Wilson, Lucy; Clostridium difficile Infection Surveillance Investigators; Centers for Disease Control and Prevention (Oxford University Press, 2013-07-29)
    Nucleic acid amplification testing (NAAT) is increasingly being adopted for diagnosis of Clostridium difficile infection (CDI). Data from 3 states conducting population-based CDI surveillance showed increases ranging from ...
  • Transmission of Vaccinia Virus, Possibly Through Sexual Contact, to a Woman at High Risk for Adverse Complications 

    Said, Maria A.; Haile, Charles; Palabindala, Venkataraman; Barker, Naomi; Myers, Robert; Thompson, Ruth; Wilson, Lucy; Allan-Martinez, Frances; Montgomery, Jay; Monroe, Benjamin; Tack, Danielle; Reynolds, Mary; Damon, Inger; Blythe, David (Oxford University Press, 2013-12-01)
    Severe adverse events, including eczema vaccinatum (EV), can result after smallpox vaccination. Persons at risk for EV include those with underlying dermatologic conditions, such as atopic dermatitis. We investigated a ...
  • Multistate Point-Prevalence Survey of Health Care–Associated Infections 

    Magill, Shelley S.; Edwards, Jonathan R.; Bamberg, Wendy; Beldavs, Zintars G.; Dumyati, Ghinwa; Kainer, Marion A.; Lynfield, Ruth; Maloney, Meghan; McAllister-Hollod, Laura; Nadle, Joelle; Ray, Susan M.; Thompson, Deborah L.; Wilson, Lucy E.; Fridkin, Scott K.; Emerging Infections Program Healthcare-Associated Infections and Antimicrobial Use Prevalence Survey Team (Massachusetts Medical Society, 2014-03-27)
    BACKGROUND Currently, no single U.S. surveillance system can provide estimates of the burden of all types of health care–associated infections across acute care patient populations. We conducted a prevalence survey in 10 ...

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