Derivative-based global sensitivity analysis for models with high-dimensional inputs and functional outputs

Author/Creator ORCID

Date

2019-02-17

Department

Program

Citation of Original Publication

Helen L. Cleaves, Alen Alexanderian, Hayley Guy, Ralph C. Smith and Meilin Yu, Derivative-based global sensitivity analysis for models with high-dimensional inputs and functional outputs, 2019, https://arxiv.org/pdf/1902.04630.pdf

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Abstract

We present a framework for derivative-based global sensitivity analysis (GSA) for models with high-dimensional input parameters and functional outputs. We combine ideas from derivative-based GSA, random eld representation via Karhunen-Loeve expansions, and adjoint- based gradient computation to provide a scalable computational framework for computing the pro- posed derivative-based GSA measures. We illustrate the strategy for a nonlinear ODE model of cholera epidemics and for elliptic PDEs with application examples from geosciences and biotrans- port