Identification and characterization of the pckA gene from Staphylococcus aureus

Author/Creator ORCID

Date

1996-06

Department

Program

Citation of Original Publication

W. H. Scovill, H. J. Schreier, and K. W. Bayles, Identification and characterization of the pckA gene from Staphylococcus aureus, J Bacteriol. 1996 Jun; 178(11): 3362–3364, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC178095/

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Abstract

The Staphylococcus aureus pckA gene was identified and characterized. A pckA mutant lacked detectable phosphoenolpyruvate carboxykinase activity and grew poorly in the absence of glucose. Both enzymatic activity and pckA promoter activity in wild-type cells grown in the absence of glucose were at least 22-fold greater than activities in cells grown in the presence of glucose.