Use of the beta-lactamase inhibitor clavulanic acid in the isolation of auxotrophic mutants of Bacillus licheniformis

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC215723/
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http://hdl.handle.net/11603/13275
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Date
1984-08
Type of Work
2 pages
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journal articles
Citation of Original Publication
P I Fields, H J Schreier, A L Saha, and R W Bernlohr, Use of the beta-lactamase inhibitor clavulanic acid in the isolation of auxotrophic mutants of Bacillus licheniformis., J Bacteriol. 1984 Aug; 159(2): 803–804, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC215723/
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Subjects
Bacillus licheniformis
beta-lactamase activity
clavulanic acid and cefotaxime
Abstract
The isolation of auxotrophic mutants of Bacillus licheniformis, a microbe containing constitutive ,β-lactamase activity, was found to be facilitated by the addition of clavulanic acid and cefotaxime during enrichment.