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    Vagal gustatory reflex circuits for intraoral food sorting behavior in the goldfish: Cellular organization and neurotransmitters

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    https://onlinelibrary.wiley.com/doi/abs/10.1002/cne.22097
    Permanent Link
    https://doi.org/10.1002/cne.22097
    http://hdl.handle.net/11603/21068
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    • UMBC Biological Sciences Department
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    Author/Creator
    Ikenaga, Takanori
    Ogura, Tatsuya
    Finger, Thomas E.
    Date
    2009-09-20
    Type of Work
    26 pages
    Text
    journal articles postprints
    Citation of Original Publication
    Takanori Ikenaga, Tatsuya Ogura and Thomas E. Finger, Vagal gustatory reflex circuits for intraoral food sorting behavior in the goldfish: Cellular organization and neurotransmitters,J Comp Neurol. (2009); 516(3): 213–225. doi:10.1002/cne.22097.
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    This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
    This is the peer reviewed version of the following article: Takanori Ikenaga, Tatsuya Ogura and Thomas E. Finger, Vagal gustatory reflex circuits for intraoral food sorting behavior in the goldfish: Cellular organization and neurotransmitters, J Comp Neurol. (2009); 516(3): 213–225. doi:10.1002/cne.22097, which has been published in final form at https://doi.org/10.1002/cne.22097. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions
    Abstract
    The sense of taste is crucial in an animal's determination as to what is edible and what is not. This gustatory function is especially important in goldfish, who utilize a sophisticated oropharyngeal sorting mechanism to separate food from substrate material. The computational aspects of this detection are carried out by the medullary vagal lobe, which is a large, laminated structure combining elements of both the gustatory nucleus of the solitary tract and the nucleus ambiguus. The sensory layers of the vagal lobe are coupled to the motor layers via a simple reflex arc. Details of this reflex circuit were investigated with histology and calcium imaging. Biocytin injections into the motor layer labeled vagal reflex interneurons that have radially directed dendrites ramifying within the layers of primary afferent terminals. Axons of reflex interneurons extend radially inward to terminate onto both vagal motoneurons and small, GABAergic interneurons in the motor layer. Functional imaging shows increases in intracellular Ca++ of vagal motoneurons following electrical stimulation in the sensory layer. These responses were suppressed under Ca++‐free conditions and by interruption of the axons bridging between the sensory and motor layers. Pharmacological experiments showed that glutamate acting via (±)‐α‐amino‐3‐hydroxy‐ 5‐ethylisoxazole‐4‐propioinc acid (AMPA)/kainate and N‐methyl‐D‐aspartic acid (NMDA) receptors mediate neurotransmission between reflex interneurons and vagal motoneurons. Thus, the vagal gustatory portion of the viscerosensory complex is linked to branchiomotor neurons of the pharynx via a glutamatergic interneuronal system.


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    Albin O. Kuhn Library & Gallery
    University of Maryland, Baltimore County
    1000 Hilltop Circle
    Baltimore, MD 21250
    www.umbc.edu/scholarworks

    Contact information:
    Email: scholarworks-group@umbc.edu
    Phone: 410-455-3021


    If you wish to submit a copyright complaint or withdrawal request, please email mdsoar-help@umd.edu.