CUL4B: Trash talking at chromatin

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https://www.cell.com/molecular-cell/fulltext/S1097-2765(11)00539-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276511005399%3Fshowall%3Dtrue

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https://doi.org/10.1016/j.molcel.2011.07.015
 http://hdl.handle.net/11603/26720

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UMBC Biological Sciences Department

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https://orcid.org/0000-0003-3923-6726

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2011-08-05

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journal articles
postprints
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Green, Erin M, and Or Gozani. “CUL4B: trash talking at chromatin.” Molecular cell vol. 43,3 (2011): 321-3. doi:10.1016/j.molcel.2011.07.015

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Abstract

In this issue, Nakagawa and Xiong (2011) reveal a mechanism targeting WDR5 for proteolysis dependent on the X-linked mental retardation gene, CUL4B. This provides a link between the stability of a chromatin factor and gene expression implicated in neurological pathogenesis.