UMBC Chemical, Biochemical & Environmental Engineering Department
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Faculty in our department focus their research in nine core areas encompassing biological, environmental, and educational research. Our department offers an undergraduate course of study leading to a B.S. in Chemical Engineering through three tracks of study: (i) Traditional Track, (ii) Biotechnology and Bioengineering Track and (iii) Environmental Engineering and Sustainability track. We also offer both M.S. and Ph.D. degrees through two different graduate programs. Details can be found on our website: http://www.umbc.edu/cbe
Recent Submissions
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UMBC faculty, alumni entrepreneurs receive record-number of MIPS awards for tech collaborations
Six UMBC faculty members have just received grants from the Maryland Industrial Partnerships (MIPS) program to develop new technologies with potential to grow the state’s economy. This is UMBC’s largest number of winning ... -
Cell-free protein synthesis: advances on production process for biopharmaceuticals and immunobiological products
(Future Science Group, 2021-01-20)Biopharmaceutical products are of great importance in the treatment or prevention of many diseases and represent a growing share of the global pharmaceutical market. The usual technology for protein synthesis (cell-based ... -
A Golden-Gate Based Cloning Toolkit to Build Violacein Pathway Libraries in Yarrowia lipolytica
(ACS Publications, 2021-01-05)Violacein is a naturally occurring anticancer therapeutic compound with deep purple color. In this work, we harnessed the modular and combinatorial feature of a Golden Gate assembly method to construct a library of violacein ... -
Investigating the evolution of water-soluble organic carbon in evaporating cloud water
(Royal Society of Chemistry, 2020-12-22)Cloud cycling plays a key role in the evolution of atmospheric particles and gases, producing secondary aerosol mass and transforming the optical properties and impacts of aerosols globally. In this study, bulk cloud water ... -
Nanocomposites for low dose gamma-ray sensor: Effect of matrix and oxidizer on the performance
(SPIE, 2019-05-14)Synthesis and crystal growth of scintillators and semiconductor materials for radiation detectors have been proven to be time consuming and very costly. Several alternative crystals such as Tl3ASSe3, TlGaSe2, Tl4HgI6, ... -
Long-term stability and efficacy of historic activated carbon (AC) deployments at diverse freshwater and marine remediation sites
A number of sites around the United States have used activated carbon (AC) amendments to remedy contaminated sediments. Variation in site-specific characteristics likely influences the long-term fate and efficacy of AC ... -
Screen Printing to Create 3D Tissue Models
(ACS Publications, 2020-11-02)3D printing has revolutionized making tissue models, but the instruments are often quite expensive, and the approach can involve heat and/or shear forces that can damage cells. As a complement to more traditional 3D printing ... -
On-Demand and Long-Term Drug Delivery from Degradable Nanocapsules
(ACS Publications, 2020-10-23)We have developed polyurethane nanocapsules as a platform for long-term delivery of drugs over weeks as well as on-demand delivery of drugs via ultrasound. We synthesized nanocapsules encapsulating either a model drug, ... -
Developments in Insulin Manufacturing Using Cell-Free Systems
The primary aim of this method is to emulate the naturally occurring mechanisms which take place in vivo, when converting preproinsulin into metabolically active insulin (4). Figure 2, displays the binding of pre-proinsulin ... -
Mechanoregulation of T-cell Function through Yap
Although tumor immunotherapy has been developed for various cancers, sustaining T-cell activation and recruitment in immunosuppressive solid tumors remains a major hurdle. T-cell function is modulated by mechanical cues, ... -
Synthetic yeast brews neuroactive compounds
(Nature, 2020-10-28)Metabolic engineering offers the flexibility to meet market demand for bioactive natural products but can be hampered when a necessary protein or intermediate is toxic. In yeast, modifying the subcellular localization of ... -
American Chemical Society honors UMBC’s Lee Blaney for commitment to mentoring student researchers
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Characterization of Met25 as a color associated genetic marker in Yarrowia lipolytica
(Elsevier, 2020-10-03)Yarrowia lipolytica offers an ideal host for biosynthesis of high value natural products and oleochemicals through metabolic engineering despite being restricted to a limited number of selective markers, and counter-selection ... -
Thermo in the Time of COVID-19: Using Improvisation to Foster Discussion and Translating the Experience to Online Learning
(Springer Nature, 2020-09-02)This paper covers teaching a graduate thermodynamics class as a seminar and using improvisational activities to foster community and discussion. The paper includes the experience of piloting improvisational activities ... -
Pavement alters delivery of sediment and fallout radionuclides to urban streams
(Elsevier, 2020-03-16)Sediment from urban impervious surfaces has the potential to be an important vector for contaminants, particularly where stormwater culverts and other buried channels draining large impervious areas exit from underground ... -
Intratumoral generation of photothermal gold nanoparticles through a vectorized biomineralization of ionic gold
(Springer Nature, 2020-09-10)Various cancer cells have been demonstrated to have the capacity to form plasmonic gold nanoparticles when chloroauric acid is introduced to their cellular microenvironment. But their biomedical applications are limited, ... -
Competitive Adsorption of As (III), As (V), and PO 4 by an Iron Oxide Impregnated Activated Carbon: Surface Complex Modeling
(Springer Nature, 2020-09-02)The objective of this study was to predict the competitive adsorption of As(III), As(V), and PO₄ by an iron oxide impregnated carbon (L-Act, 9% Fe(III) amorphous iron oxide) over a range of environmental conditions using ... -
Design and measurements of n for the multicomponent semiconductor
(SPIE, 2020-08-20)A great deal of research has been performed on refractive index n and extinction coefficient k due to varieties of applications in optical industries. The dispersion equation is described for the photons of varying energies ... -
Comprehensive Analysis of Aspergillus nidulans PKA Phosphorylome Identifies a Novel Mode of CreA Regulation
(American Society for Microbiology, 2019-04)The fungal cell-wall integrity signaling (CWIS) pathway regulates cellular response to environmental stress to enable wall repair and resumption of normal growth. This complex, interconnected, pathway has been only partially ... -
Dynamic transcriptomic and phosphoproteomic analysis during cell wall stress in Aspergillus nidulans
(ASBMB Publications, 2020-08-01)The fungal cell-wall integrity signaling (CWIS) pathway regulates cellular response to environmental stress to enable wall repair and resumption of normal growth. This complex, interconnected, pathway has been only partially ...