UMBC Chemical, Biochemical & Environmental Engineering Department
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Faculty in our department focus their research in nine core areas encompassing biological, environmental, and educational research. Our department offers an undergraduate course of study leading to a B.S. in Chemical Engineering through three tracks of study: (i) Traditional Track, (ii) Biotechnology and Bioengineering Track and (iii) Environmental Engineering and Sustainability track. We also offer both M.S. and Ph.D. degrees through two different graduate programs. Details can be found on our website: http://www.umbc.edu/cbe
Recent Submissions
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Sensor Techknowledge: Sensors for Process Development: A Practical Guide
(UMBC Center for Advanced Sensor Technology and Department of Biochemical and Environmental Engineering, 2020-07-05) -
Self‐healing biomaterials: The next generation is nano
(Wiley, 2020-05-02)The U.S. Agency for Healthcare Research and Quality estimates that there are over 1 million total hip and total knee replacements each year in the U.S. alone. Twenty five percent of those implants will experience aseptic ... -
Exotic Electrophiles in Chlorinated and Chloraminated Water: When Conventional Kinetic Models and Reaction Pathways Fall Short
(ACS Publications, 2020-05-14)Halogenation and oxidation of organic matter in chlorinated and chloraminated water are typically attributed to the most abundant electrophiles present. This interpretation sometimes fails to explain laboratory observations, ... -
Biotechnological production of flavonoids: an update on plant metabolic engineering, microbial host selection and genetically encoded biosensors
Flavonoids represent a diversified family of phenylpropanoid-derived plant secondary metabolites. They are widely found in fruits, vegetables and medicinal herbs and plants. There has been increasing interest on flavonoids ... -
Dynamics of microbial competition, commensalism and cooperation and its implications for coculture and microbiome engineering
(2020-03-06)Microbial consortium is a complex adaptive system with higher order dynamic characteristics that are not present by individual members. To accurately predict the social interactions, we formulate a set of unified unstructural ... -
Ex situ determination of freely dissolved concentrations of hydrophobic organic chemicals in sediments and soils: basis for interpreting toxicity and assessing bioavailability, risks and remediation necessity
(Springer Nature, 2020-04-20)The freely dissolved concentration (Cfree) of hydrophobic organic chemicals in sediments and soils is considered the driver behind chemical bioavailability and, ultimately, toxic effects in benthic organisms. Therefore, ... -
Branch point control at malonyl-CoA node: A computational framework to uncover the design principles of an ideal genetic-metabolic switch
(Elsevier, 2020-04-24)Living organism is an intelligent system coded by hierarchically-organized information to perform precisely-controlled biological functions. Biophysical models are important tools to uncover the design rules underlying ... -
Chemical and biological sensing using polarity of material
(SPIE, 2020-04-24)Polarity is very important in developing materials with colossal dielectric. To meet the demands for the tunable devices and high dielectric parallel plate capacitors, several perovskites such as CaCu₃Ti₄O₁₂ (CCTO), ... -
Inputs and outputs for MINEQL modelling of Cu, Mn, Fe
(2020-04-20) -
Small-angle X-ray scattering characterization of a β-amyloid model in phantoms
Objective We present a method to prepare an amyloid model at scalable quantities for phantom studies to evaluate small-angle x-ray scattering systems for amyloid detection. Two amyloid models were made from a plasma protein ... -
Refactoring Ehrlich Pathway for High-Yield 2-Phenylethanol Production in Yarrowia lipolytica
(ACS Publications, 2020-03-05)Efficient microbial synthesis of chemicals requires the coordinated supply of precursors and cofactors to maintain cell growth and product formation. Substrates with different entry points into the metabolic network have ... -
Applying chemical reaction transition theory to predict the latent transmission dynamics of coronavirus outbreak in China
(2020-02-25)The recent outbreak of the Covid-19 suggests a rather long latent phase that precludes public health officials to predict the pandemic transmission on time. Here we apply mass action laws and chemical transition theory to ... -
On Aerosol Liquid Water and Sulfate Associations: The Potential for Fine Particulate Matter Biases
(MDPI, 2020-02-12)In humid locations of the Eastern U.S., sulfate is a surrogate for aerosol liquid water (ALW), a poorly measured particle constituent. Regional and seasonal variation in ALW–sulfate relationships offers a potential explanation ... -
Debottlenecking mevalonate pathway for antimalarial drug precursor amorphadiene biosynthesis in Yarrowia lipolytica
(Elsevier B.V., 2020-06-10)World Health Organization reports that half of the population in developing countries are at risk of malaria infection. Artemisinin, the most potent anti-malaria drug, is a sesquiterpene endoperoxide extracted from the ... -
Real‐time dissolved carbon dioxide monitoring II: Surface aeration intensification for efficient CO2 removal in shake flasks and mini‐bioreactors leads to superior growth and recombinant protein yields
(Wiley Online Library, 2019-12-13)Mass transfer is known to play a critical role in bioprocess performance and henceforth monitoring dissolved O₂ (DO) and dissolved CO₂ (dCO₂) is of paramount importance. At bioreactor level these parameters can be monitored ... -
Real‐time dissolved carbon dioxide monitoring I: Application of a novel in situ sensor for CO2 monitoring and control
(Wiley Online Library, 2019-12-16)Dissolved carbon dioxide (dCO₂) is a well‐known critical parameter in bioprocesses due to its significant impact on cell metabolism and on product quality attributes.Processes run at small‐scale faces many challenges due ... -
Enhanced symbolic regression to infer biochemical network models
(2019-07-14)Biological systems can be represented as complex networks illustrating the relationships and connections among biochemical species. Complex networks can uncover vital information regarding specific pathways or network ... -
Reporter Scaffolds for Clinically Relevant Cell Transplantation Studies
(Springer US, 2019-11-04)There are a number of cell therapies that are either in clinical trials or moving toward clinical trials, particularly for diseases of the retina. One of the challenges with cell therapies is tracking the status of cells ... -
Development of a Novel Equilibrium Passive Sampling Devicefor Methylmercury in Sediment and Soil Porewaters
(Society of Environmental Toxicology and Chemistry, 2019-11-06)We explored the concept of equilibrium passive sampling for methylmercury (MeHg) using the strategy developedfor hydrophobic organic chemicals. Passive sampling should allow prediction of the concentration of the chemically ... -
The Acidity of Atmospheric Particles and Clouds
(EGU, 2019-10-18)Acidity, defined as pH, is a central component of aqueous chemistry. In the atmosphere, the acidity of condensed phases (aerosol particles, cloud water, and fog droplets) governs the phase partitioning of semi-volatile ...
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