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    Assessment of spatial response initiation in the Morris water maze

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    Coppola Thesis (353.2Kb)
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    http://library.towson.edu/digital/collection/etd/id/57649
    Permanent Link
    http://hdl.handle.net/11603/5226
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    • Towson University Graduate Theses and Dissertations
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    Author/Creator
    Coppola, Jessica Marie
    Date
    2017-09-11
    2017-05
    Type of Work
    application/pdf
    v, 30 pages
    Text
    theses
    Department
    Towson University. Department of Psychology
    Abstract
    Two facets of Obsessive Compulsive Disorder are obsessions and compulsions. Compulsions are strong, maladaptive habit behaviors exhibited to reduce obsessions, or unwanted thoughts. Compulsions in OCD, in part, are a product of dysfunctional communication between the striatum/habit memory system and higher areas of cortex which creates strong habit responses that are unable to be inhibited. Successful behavioral rodent models for these strong compulsive habits have been created through overtraining and repeated trials. The present study intended to create a behavioral paradigm of compulsive checking behavior in rodents through rats receiving four, eight, and sixteen days of training on a platform location in the Morris water maze. Eight and sixteen days of training were intended to produce overtraining and spatial response initiation. Results are discussed in terms of the animals’ self-initiated spatial response towards a previously learned location after being placed in a novel location.


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    Towson University
    8000 York Road
    Towson, Maryland 21252

    Website:
    www.towson.edu

    Contact Info:
    azukowski@towson.edu
    410-704-5318
    http://libraries.towson.edu/md-soar


    If you wish to submit a copyright complaint or withdrawal request, please email mdsoar-help@umd.edu.