Determination of the residual efficacy of broflanilide (VECTRON™ T500) insecticide for indoor residual spraying in a semi-field setting in Ethiopia

Date

2025-02-13

Department

Program

Citation of Original Publication

Simma, Eba Alemayehu, Habtamu Zegeye, Geremew Muleta Akessa, Yehenew G. Kifle, Endalew Zemene, Teshome Degefa, and Delenasaw Yewhalaw. "Determination of the Residual Efficacy of Broflanilide (VECTRON™ T500) Insecticide for Indoor Residual Spraying in a Semi-Field Setting in Ethiopia." Malaria Journal 24, no. 1 (February 13, 2025): 44. https://doi.org/10.1186/s12936-024-05239-9.

Rights

Attribution-NonCommercial-NoDerivatives 4.0 International

Abstract

The rotational use of insecticides with diverse modes of action in indoor residual spraying (IRS) is pivotal for enhancing malaria vector control and addressing insecticide resistance. A key factor in national malaria vector control/elimination programmes is the rate at which these insecticides decay. VECTRON™ T500, with broflanilide as its active ingredient, is a recently developed candidate insecticide formulation which has shown promising results in certain phase II experimental hut trials. However, its residual efficacy across different settings has not been thoroughly investigated. This study evaluated the efficacy of VECTRON™ T500 on various wall surfaces (mud, dung, paint, and cement) and assessed its decay rates over time in Ethiopia.