Developments in Insulin Manufacturing Using Cell-Free Systems

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dc.contributor.authorBorhani, Shayan
dc.contributor.authorGurramkonda, Chandrasekhar
dc.contributor.authorFrey, Douglas
dc.contributor.authorTolosa, Leah
dc.contributor.authorSwartz, James
dc.contributor.authorRao, Govind
dc.date.accessioned2020-11-19T18:53:44Z
dc.date.available2020-11-19T18:53:44Z
dc.description.abstractThe primary aim of this method is to emulate the naturally occurring mechanisms which take place in vivo, when converting preproinsulin into metabolically active insulin (4). Figure 2, displays the binding of pre-proinsulin to a CM HiTrap FF column (pH 3.0) followed by cleavage and threonine addition to the terminal B29 residue. The final product is then eluted using a linear salt gradient.en_US
dc.description.urihttps://elrig.org/downloads/ddd/3040_Developments_in_Insulin_Manufacturing_Using_Cell_Free_Systems.pdfen_US
dc.format.extent1 pageen_US
dc.genrepostersen_US
dc.identifierdoi:10.13016/m29vfd-wr5o
dc.identifier.citationShayan Borhani et al., Developments in Insulin Manufacturing Using Cell-Free Systems, https://elrig.org/downloads/ddd/3040_Developments_in_Insulin_Manufacturing_Using_Cell_Free_Systems.pdfen_US
dc.identifier.urihttp://hdl.handle.net/11603/20102
dc.language.isoen_USen_US
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Center for Advanced Sensor Technology (CAST)
dc.relation.ispartofUMBC Faculty Collection
dc.relation.ispartofUMBC Student Collection
dc.relation.ispartofUMBC Chemical, Biochemical & Environmental Engineering Department
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.subjectinsulinen_US
dc.subjectcell free systemsen_US
dc.subjectdiabetesen_US
dc.titleDevelopments in Insulin Manufacturing Using Cell-Free Systemsen_US
dc.typeTexten_US

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