Developments in Insulin Manufacturing Using Cell-Free Systems

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dc.contributor.authorBorhani, Shayan
dc.contributor.authorGurramkonda, Chandrasekhar
dc.contributor.authorFrey, Douglas
dc.contributor.authorTolosa, Leah
dc.contributor.authorSwartz, James
dc.contributor.authorRao, Govind
dc.date.accessioned2020-11-19T18:53:44Z
dc.date.available2020-11-19T18:53:44Z
dc.description.abstractThe primary aim of this method is to emulate the naturally occurring mechanisms which take place in vivo, when converting preproinsulin into metabolically active insulin (4). Figure 2, displays the binding of pre-proinsulin to a CM HiTrap FF column (pH 3.0) followed by cleavage and threonine addition to the terminal B29 residue. The final product is then eluted using a linear salt gradient.en
dc.description.urihttps://elrig.org/downloads/ddd/3040_Developments_in_Insulin_Manufacturing_Using_Cell_Free_Systems.pdfen
dc.format.extent1 pageen
dc.genrepostersen
dc.identifierdoi:10.13016/m29vfd-wr5o
dc.identifier.citationShayan Borhani et al., Developments in Insulin Manufacturing Using Cell-Free Systems, https://elrig.org/downloads/ddd/3040_Developments_in_Insulin_Manufacturing_Using_Cell_Free_Systems.pdfen
dc.identifier.urihttp://hdl.handle.net/11603/20102
dc.language.isoenen
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Center for Advanced Sensor Technology (CAST)
dc.relation.ispartofUMBC Faculty Collection
dc.relation.ispartofUMBC Student Collection
dc.relation.ispartofUMBC Chemical, Biochemical & Environmental Engineering Department
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.subjectinsulinen
dc.subjectcell free systemsen
dc.subjectdiabetesen
dc.titleDevelopments in Insulin Manufacturing Using Cell-Free Systemsen
dc.typeTexten

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