Epidemiology of Antibiotic Use for Urinary Tract Infection in Nursing Home Residents
| dc.contributor.author | Thompson, Nicola D. | |
| dc.contributor.author | Penna, Austin | |
| dc.contributor.author | Eure, Taniece R. | |
| dc.contributor.author | Bamberg, Wendy M. | |
| dc.contributor.author | Wilson, Lucy E. | |
| dc.contributor.author | et al | |
| dc.date.accessioned | 2023-08-01T21:32:17Z | |
| dc.date.available | 2023-08-01T21:32:17Z | |
| dc.date.issued | 2019-12-27 | |
| dc.description | Authors: - Nicola D. Thompson, Austin Penna, Taniece R. Eure, Wendy M. Bamberg, Grant Barney, Devra Barter, Paula Clogher, Malini B. DeSilva, Ghinwa Dumyati, Erin Epson, Linda Frank, Deborah Godine, Lourdes Irizarry, Marion A. Kainer, Linda Li, Ruth Lynfield , J.P. Mahoehney, Joelle Nadle, Valerie Ocampo, Lewis Perry, Susan M. Ray, Sarah Shrum Davis, Marla Sievers, Lucy E. Wilson, Alexia Y. Zhang, Nimalie D. Stone, Shelley S. Magill | |
| dc.description.abstract | Objectives Describe antibiotic use for urinary tract infection (UTI) among a large cohort of US nursing home residents. Design Analysis of data from a multistate, 1-day point prevalence survey of antimicrobial use performed between April and October 2017. Setting and participants Residents of 161 nursing homes in 10 US states of the Emerging Infections Program (EIP). Methods EIP staff reviewed nursing home medical records to collect data on systemic antimicrobial drugs received by residents, including therapeutic site, rationale for use, and planned duration. For drugs with the therapeutic site documented as urinary tract, pooled mean and nursing home–specific prevalence rates were calculated per 100 nursing home residents, and proportion of drugs by selected characteristics were reported. Data were analyzed in SAS, version 9.4. Results Among 15,276 residents, 407 received 424 antibiotics for UTI. The pooled mean prevalence rate of antibiotic use for UTI was 2.66 per 100 residents; nursing home–specific rates ranged from 0 to 13.6. One-quarter of antibiotics were prescribed for UTI prophylaxis, with a median planned duration of 111 days compared with 7 days when prescribed for UTI treatment (P < .001). Fluoroquinolones were the most common (18%) drug class used. Conclusions and Implications One in 38 residents was receiving an antibiotic for UTI on a given day, and nursing home–specific prevalence rates varied by more than 10-fold. UTI prophylaxis was common with a long planned duration, despite limited evidence to support this practice among older persons in nursing homes. The planned duration was ≥7 days for half of antibiotics prescribed for treatment of a UTI. Fluoroquinolones were the most commonly used antibiotics, despite their association with significant adverse events, particularly in a frail and older adult population. These findings help to identify priority practices for nursing home antibiotic stewardship. | en_US |
| dc.description.uri | https://www.sciencedirect.com/science/article/abs/pii/S1525861019308114 | en_US |
| dc.format.extent | 6 pages | en_US |
| dc.genre | journal articles | en_US |
| dc.identifier | doi:10.13016/m2de7v-xnan | |
| dc.identifier.citation | Thompson, Nicola D., Austin Penna, Taniece R. Eure, Wendy M. Bamberg, Grant Barney, Devra Barter, Paula Clogher, et al. “Epidemiology of Antibiotic Use for Urinary Tract Infection in Nursing Home Residents.” Journal of the American Medical Directors Association, Infection in Post-Acute and Long-Term Care, 21, no. 1 (January 1, 2020): 91–96. https://doi.org/10.1016/j.jamda.2019.11.009. | en_US |
| dc.identifier.uri | https://doi.org/10.1016/j.jamda.2019.11.009 | |
| dc.identifier.uri | http://hdl.handle.net/11603/29008 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Elsevier | en_US |
| dc.relation.isAvailableAt | The University of Maryland, Baltimore County (UMBC) | |
| dc.relation.ispartof | UMBC Emergency Health Services Department Collection | |
| dc.relation.ispartof | A. All Hilltop Institute (UMBC) Works | |
| dc.relation.ispartof | UMBC School of Public Policy | |
| dc.rights | This work was written as part of one of the author's official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law. | en_US |
| dc.rights | Public Domain Mark 1.0 | * |
| dc.rights.uri | http://creativecommons.org/publicdomain/mark/1.0/ | * |
| dc.title | Epidemiology of Antibiotic Use for Urinary Tract Infection in Nursing Home Residents | en_US |
| dc.type | Text | en_US |