Design and rationale of the Botswana Smoking Abstinence Reinforcement Trial: a protocol for a stepped-wedge cluster randomized trial
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Citation of Original Publication
Bada, Florence, Megan E. Mansfield, Lillian Okui, Milton Montebatsi, Carlo DiClemente, Roy Tapera, Kaizer Ikgopoleng, et al. “Design and Rationale of the Botswana Smoking Abstinence Reinforcement Trial: A Protocol for a Stepped-Wedge Cluster Randomized Trial.” Implementation Science Communications 5, no. 1 (May 8, 2024): 53. https://doi.org/10.1186/s43058-024-00588-7.
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CC BY 4.0 DEED Attribution 4.0 International
Abstract
With expanded and sustained availability of HIV treatment resulting in substantial improvements in life expectancy, the need to address modifiable risk factors associated with leading causes of death among people living with HIV/AIDS (PLWH), such as tobacco smoking, has increased. Tobacco use is highly prevalent among PLWH, especially in southern Africa, where HIV is heavily concentrated, and many people who smoke would like to quit but are unable to do so without assistance. SBIRT (Screening, Brief Intervention and Referral to Treatment) is a well-established evidence-based approach successful at supporting smoking cessation in a variety of settings. Varenicline is efficacious in supporting smoking cessation. We intend to assess the effectiveness of SBIRT and varenicline on smoking cessation among PLWH in Botswana and the effectiveness of our implementation.