A parallel simulation of the evolution of transcription factor binding sites
| dc.contributor.author | Forder, Robert | |
| dc.date.accessioned | 2018-10-26T14:27:30Z | |
| dc.date.available | 2018-10-26T14:27:30Z | |
| dc.date.issued | 2011-05-27 | |
| dc.description.abstract | The analysis of transcription factor binding motifs may aid in understanding the process by which transcription factors recognize their binding sites. We wish to investigate the likelihood that transcription factors use correlation between positions in potential binding sites as a criteria for recognition. We implement a genetic algorithm in parallel using a simple server-client organization to simulate the evolution of these binding sites. We then evaluate the performance of this application and conclude that exhibits excellent speedup and efficiency. | en_US |
| dc.description.sponsorship | The hardware used in the computational studies is part of the UMBC High Performance Computing Facility (HPCF). The facility is supported by the U.S. National Science Foundation through the MRI program (grant no. CNS–0821258) and the SCREMS program (grant no. DMS–0821311), with additional substantial support from the University of Maryland, Baltimore County (UMBC). See www.umbc.edu/hpcf for more information on HPCF and the projects using its resources. | en_US |
| dc.description.uri | https://userpages.umbc.edu/~gobbert/papers/ForderMath627.pdf | en_US |
| dc.format.extent | 7 pages | en_US |
| dc.genre | technical report | en_US |
| dc.identifier | doi:10.13016/M2W669C73 | |
| dc.identifier.uri | http://hdl.handle.net/11603/11746 | |
| dc.language.iso | en_US | en_US |
| dc.relation.isAvailableAt | The University of Maryland, Baltimore County (UMBC) | |
| dc.relation.ispartof | UMBC Mathematics Department Collection | |
| dc.relation.ispartofseries | HPCF Technical Report;HPCF-2011-1 | |
| dc.rights | This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author. | |
| dc.subject | parallel simulation | en_US |
| dc.subject | evolution | en_US |
| dc.subject | transcription factor binding motifs | en_US |
| dc.subject | binding sites | en_US |
| dc.subject | UMBC High Performance Computing Facility (HPCF) | en_US |
| dc.title | A parallel simulation of the evolution of transcription factor binding sites | en_US |
| dc.type | Text | en_US |