Protein Image Alignment via Piecewise Affine Transformations
| dc.contributor.author | Potra, Florian A. | |
| dc.contributor.author | Liu, Xing | |
| dc.contributor.author | Seillier-Moiseiwitsch, Françoise | |
| dc.contributor.author | Roy, Anindya | |
| dc.contributor.author | Hang, Yaming | |
| dc.contributor.author | Marten, Mark R. | |
| dc.contributor.author | Raman, Babu | |
| dc.contributor.author | Whisnant, Carol | |
| dc.date.accessioned | 2019-02-11T15:47:44Z | |
| dc.date.available | 2019-02-11T15:47:44Z | |
| dc.description.abstract | We present a new approach for aligning families of 2D gels. Instead of choosing one of the gels as reference and performing a pairwise alignment, we construct an ideal gel that is representative of the entire family and obtain a set of piecewise affine transformations that optimally align each gel of the family to the ideal gel. The coefficients defining the transformations as well as the ideal landmarks are obtained as the solution of a large-scale quadratic programming problem that can be solved efficiently by interior-point methods. | en_US |
| dc.description.sponsorship | This research was partially funded by a grant (R01 GM075298) from the joint NSF-NIGMS program in mathematical biology. | en_US |
| dc.description.uri | https://www.liebertpub.com/doi/10.1089/cmb.2006.13.614 | en_US |
| dc.format.extent | 17 pages | en_US |
| dc.genre | journal articles postprints | en_US |
| dc.identifier | doi:10.13016/m29lyx-jazu | |
| dc.identifier.citation | Florian A. Potra ,Xing Liu, Françoise Seillier-Moiseiwitsch, Anindya Roy, Yaming Hang, Mark R. Marten, Babu Raman, Carol Whisnant, Protein Image Alignment via Piecewise Affine Transformations, Journal of Computational Biology, Vol. 13, No. 3 , 2006 , DOI : https://doi.org/10.1089/cmb.2006.13.614 | en_US |
| dc.identifier.uri | https://doi.org/10.1089/cmb.2006.13.614 | |
| dc.identifier.uri | http://hdl.handle.net/11603/12759 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Mary Ann Liebert, Inc., publishers | en_US |
| dc.relation.isAvailableAt | The University of Maryland, Baltimore County (UMBC) | |
| dc.relation.ispartof | UMBC Chemical, Biochemical & Environmental Engineering Department Collection | |
| dc.relation.ispartof | UMBC Faculty Collection | |
| dc.relation.ispartof | UMBC Mathematics and Statistics Department | |
| dc.rights | This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author. | |
| dc.rights | Final publication is available from Mary Ann Liebert, Inc., publishers http://dx.doi.org/10.1089/cmb.2006.13.614 | |
| dc.subject | image alignment registration | en_US |
| dc.subject | two-dimensional gels | en_US |
| dc.subject | affine transformations | en_US |
| dc.subject | interior-point methods | en_US |
| dc.subject | quadratic programming | en_US |
| dc.title | Protein Image Alignment via Piecewise Affine Transformations | en_US |
| dc.type | Text | en_US |