Visual Deficits and Dysfunctions Associated with Traumatic Brain Injury: A Systematic Review and Meta-analysis

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dc.contributor.authorMerezhinskaya, Natalya
dc.contributor.authorMallia, Rita K.
dc.contributor.authorPark, DoHwan
dc.contributor.authorBryden, Daniel W.
dc.contributor.authorMathur, Karan
dc.contributor.authorBarker II, Felix M
dc.date.accessioned2019-10-11T14:38:38Z
dc.date.available2019-10-11T14:38:38Z
dc.date.issued2019-05-04
dc.description.abstractSIGNIFICANCE This study reports prevalence data combined independently for accommodative dysfunction, convergence insufficiency, visual field loss, and visual acuity loss in patients with traumatic brain injury in the absence of eye injury. OBJECTIVE The objective of this study was to conduct a systematic review and meta-analysis to determine the prevalence rates of accommodative dysfunction, convergence insufficiency, visual field loss, and visual acuity loss in TBI patients without concomitant eye injury. DATA SOURCES The data sources used in this study were PubMed, EMBASE, EBSCO, and Cochrane Library. STUDY APPRAISAL AND SYNTHESIS METHODS Publications reporting the prevalence of diagnosed accommodative dysfunction, convergence insufficiency, visual field loss, or visual acuity loss to the level of legal blindness in TBI patients of any age were included. Univariate metaregression analyses and subgroup analyses were performed to account for statistical heterogeneity. RESULTS Twenty-two eligible publications were identified across the four visual conditions. Random-effects models yielded combined prevalence estimates: accommodative dysfunction (42.8; 95% confidence interval [CI], 31.3 to 54.7), convergence insufficiency (36.3%; 95% CI, 28.2 to 44.9%), visual field loss (18.2%; 95% CI, 10.6 to 27.1%), and visual acuity loss (0.0%; 95% CI, 0.0 to 1.1%). Metaregression and subgroup analyses revealed that visual field loss was significantly more prevalent in moderate to severe (39.8%; 95% CI, 29.8 to 50.3%) compared with mild TBI (6.6%; 95% CI, 0 to 19.5%). CONCLUSIONS AND IMPLICATIONS OF KEY FINDINGS This study demonstrates that accommodative dysfunction, convergence insufficiency, and visual field loss are common sequelae of TBI. Prospective longitudinal research with rigorous and uniform methodology is needed to better understand short- and long-term effects of TBI on the vision system.en_US
dc.description.sponsorshipThe Vision Center of Excellenceen_US
dc.description.urihttps://journals.lww.com/optvissci/Fulltext/2019/08000/Visual_Deficits_and_Dysfunctions_Associated_with.2.aspxen_US
dc.format.extent14 pagesen_US
dc.genrejournal articlesen_US
dc.identifierdoi:10.13016/m2dl5e-ngku
dc.identifier.citationMerezhinskaya, Natalya; Mallia, Rita K.; Park, DoHwan; Bryden, Daniel W.; Mathur, Karan; Barker, Felix M. II; Visual Deficits and Dysfunctions Associated with Traumatic Brain Injury: A Systematic Review and Meta-analysis; Optometry and Vision Science 96,8; doi: 10.1097/OPX.0000000000001407en_US
dc.identifier.urihttp://dx.doi.org//10.1097/OPX.0000000000001407
dc.identifier.urihttp://hdl.handle.net/11603/15855
dc.language.isoen_USen_US
dc.publisherAmerican Academy of Optometryen_US
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Mathematics Department Collection
dc.relation.ispartofUMBC Faculty Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.rightsAttribution 4.0 International (CC BY 4.0)*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectmeta-analysisen_US
dc.subjectconcomitant eye injuryen_US
dc.subjectaccommodative dysfunctionen_US
dc.subjectconvergence insufficiencyen_US
dc.subjectvisual acuity lossen_US
dc.subjectUnivariate metaregressionen_US
dc.subjectstatistical heterogeneityen_US
dc.subjectcommon sequelaeen_US
dc.titleVisual Deficits and Dysfunctions Associated with Traumatic Brain Injury: A Systematic Review and Meta-analysisen_US
dc.typeTexten_US

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