A new rRNA processing mutant of Saccharomyces cerevisiae
| dc.contributor.author | Lindahl, L. | |
| dc.contributor.author | Archer, R. H. | |
| dc.contributor.author | Zengel, J. M. | |
| dc.date.accessioned | 2019-06-06T16:18:31Z | |
| dc.date.available | 2019-06-06T16:18:31Z | |
| dc.date.issued | 1992-01-25 | |
| dc.description.abstract | We have identified from a collection of temperature sensitive yeast mutants strains which fail to process rRNA normally. Characterization of one such mutant is reported here. This strain accumulates increased amounts of the 35S primary transcript, '24S' molecules extending from the transcription start site to the 5.8S region, and two classes of 5.8S rRNA with 5' extensions of 7 and 149 bases, respectively. We show that this pleiotropic change in the rRNA processing pattern is due to a single mutation. Possible models for the function of the mutated gene are discussed. | en_US |
| dc.description.sponsorship | This work was supported by a research grant from the National Institute for Allergy and Infectious Diseases. | en_US |
| dc.description.uri | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC310369/ | en_US |
| dc.format.extent | 7 pages | en_US |
| dc.genre | journal articles | en_US |
| dc.identifier | doi:10.13016/m2hsl7-nlvd | |
| dc.identifier.citation | L Lindahl, R H Archer, and J M Zengel, A new rRNA processing mutant of Saccharomyces cerevisiae, Nucleic Acids Res. 1992 Jan 25; 20(2): 295–301. doi: 10.1093/nar/20.2.295 | en_US |
| dc.identifier.uri | https://dx.doi.org/10.1093%2Fnar%2F20.2.295 | |
| dc.identifier.uri | http://hdl.handle.net/11603/14027 | |
| dc.language.iso | en_US | en_US |
| dc.publisher | Oxford University Press | en_US |
| dc.relation.isAvailableAt | The University of Maryland, Baltimore County (UMBC) | |
| dc.relation.ispartof | UMBC Biological Sciences Department Collection | |
| dc.relation.ispartof | UMBC Faculty Collection | |
| dc.rights | This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author. | |
| dc.subject | Saccharomyces cerevisiae | en_US |
| dc.subject | rRNA | en_US |
| dc.subject | mutant | en_US |
| dc.title | A new rRNA processing mutant of Saccharomyces cerevisiae | en_US |
| dc.type | Text | en_US |
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