A new rRNA processing mutant of Saccharomyces cerevisiae

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dc.contributor.authorLindahl, L.
dc.contributor.authorArcher, R. H.
dc.contributor.authorZengel, J. M.
dc.date.accessioned2019-06-06T16:18:31Z
dc.date.available2019-06-06T16:18:31Z
dc.date.issued1992-01-25
dc.description.abstractWe have identified from a collection of temperature sensitive yeast mutants strains which fail to process rRNA normally. Characterization of one such mutant is reported here. This strain accumulates increased amounts of the 35S primary transcript, '24S' molecules extending from the transcription start site to the 5.8S region, and two classes of 5.8S rRNA with 5' extensions of 7 and 149 bases, respectively. We show that this pleiotropic change in the rRNA processing pattern is due to a single mutation. Possible models for the function of the mutated gene are discussed.en
dc.description.sponsorshipThis work was supported by a research grant from the National Institute for Allergy and Infectious Diseases.en
dc.description.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC310369/en
dc.format.extent7 pagesen
dc.genrejournal articlesen
dc.identifierdoi:10.13016/m2hsl7-nlvd
dc.identifier.citationL Lindahl, R H Archer, and J M Zengel, A new rRNA processing mutant of Saccharomyces cerevisiae, Nucleic Acids Res. 1992 Jan 25; 20(2): 295–301. doi: 10.1093/nar/20.2.295en
dc.identifier.urihttps://dx.doi.org/10.1093%2Fnar%2F20.2.295
dc.identifier.urihttp://hdl.handle.net/11603/14027
dc.language.isoenen
dc.publisherOxford University Pressen
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Biological Sciences Department Collection
dc.relation.ispartofUMBC Faculty Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.subjectSaccharomyces cerevisiaeen
dc.subjectrRNAen
dc.subjectmutanten
dc.titleA new rRNA processing mutant of Saccharomyces cerevisiaeen
dc.typeTexten

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