The NanDeSyn database for Nannochloropsis systems and synthetic biology

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dc.contributor.authorGong, Yanhai
dc.contributor.authorKang, Nam Kyu
dc.contributor.authorKim, Young Uk
dc.contributor.authorWang, Zengbin
dc.contributor.authorWei, Li
dc.contributor.authorXin, Yi
dc.contributor.authorShen, Chen
dc.contributor.authorWang, Qintao
dc.contributor.authorYou, Wuxin
dc.contributor.authorLim, Jong-Min
dc.contributor.authorJeong, Seok Won
dc.contributor.authorPark, Youn-Il
dc.contributor.authorOh, Hee-Mock
dc.contributor.authorChang, Yong Keun
dc.contributor.authorPan, Kehou
dc.contributor.authorPoliner, Eric
dc.contributor.authorYang, Guanping
dc.contributor.authorLi-Beisson, Yonghua
dc.contributor.authorLi, Yantao
dc.contributor.authorHu, Qiang
dc.contributor.authorPoetsch, Ansgar
dc.contributor.authorFarre, Eva M.
dc.contributor.authorJeong, Won-Joong
dc.contributor.authorJeong, Byeong-ryool
dc.contributor.authorXu, Jian
dc.date.accessioned2020-12-08T19:57:30Z
dc.date.available2020-12-08T19:57:30Z
dc.date.issued2020-10-25
dc.description.abstractNannochloropsis species, unicellular industrial oleaginous microalgae, are model organisms for microalgal systems and synthetic biology. To facilitate community‐based annotation and mining of the rapidly accumulating functional genomics resources, we have initiated an international consortium and present a comprehensive multi‐omics resource database named Nannochloropsis Design and Synthesis (NanDeSyn; http://nandesyn.single‐cell.cn). Via the Tripal toolkit, it features user‐friendly interfaces hosting genomic resources with gene annotations and transcriptomic and proteomic data for six Nannochloropsis species, including two updated genomes of Nannochloropsis oceanica IMET1 and Nannochloropsis salina CCMP1776. Toolboxes for search, Blast, synteny view, enrichment analysis, metabolic pathway analysis, a genome browser, etc. are also included. In addition, functional validation of genes is indicated based on phenotypes of mutants and relevant bibliography. Furthermore, epigenomic resources are also incorporated, especially for sequencing of small RNAs including microRNAs and circular RNAs. Such comprehensive and integrated landscapes of Nannochloropsis genomics and epigenomics will promote and accelerate community efforts in systems and synthetic biology of these industrially important microalgae.en_US
dc.description.sponsorshipGlobal Frontier Project funded by the Ministry of Science and ICT, Republic of Korea. Grant Numbers: ABC‐2010‐0029728, ABC‐2011‐0031343, ABC‐2011‐0031350 Natural Science Foundation of Shandong Province. Grant Number: ZR2019QC012 National Natural Science Foundation of China. Grant Number: 31900071 Ministry of Science and Technology of China. Grant Number: 2018YFA0902502en_US
dc.description.urihttps://onlinelibrary.wiley.com/doi/10.1111/tpj.15025en_US
dc.format.extent30 pagesen_US
dc.genrejournal articles preprintsen_US
dc.identifierdoi:10.13016/m2xsxd-4lkb
dc.identifier.citationYanhai Gong Nam K. Kang Young U. Kim et al., The NanDeSyn database for Nannochloropsis systems and synthetic biology, DOI: https://doi.org/10.1111/tpj.15025en_US
dc.identifier.urihttps://doi.org/10.1111/tpj.15025
dc.identifier.urihttp://hdl.handle.net/11603/20206
dc.language.isoen_USen_US
dc.publisherWileyen_US
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Department of Marine Biotechnology
dc.relation.ispartofUMBC Faculty Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.rightsThis is the pre-peer reviewed version of the following article: Yanhai Gong Nam K. Kang Young U. Kim et al., The NanDeSyn database for Nannochloropsis systems and synthetic biology, DOI: https://doi.org/10.1111/tpj.15025, which has been published in final form at https://doi.org/10.1111/tpj.15025. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
dc.titleThe NanDeSyn database for Nannochloropsis systems and synthetic biologyen_US
dc.typeTexten_US

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