Neuron absorption study and mid-IR optical excitations

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dc.contributor.authorGuo, Dingkai
dc.contributor.authorChen, Xing
dc.contributor.authorVadala, Shilpa
dc.contributor.authorLeach, Jennie
dc.contributor.authorKostov, Yordan
dc.contributor.authorBewley, William W.
dc.contributor.authorKim, Chul-Soo
dc.contributor.authorKim, Mijin
dc.contributor.authorCanedy, Chadwick L.
dc.contributor.authorMerritt, Charles D.
dc.contributor.authorVurgaftman, Igor
dc.contributor.authorMeyer, Jerry R.
dc.contributor.authorChoa, Fow-Sen
dc.date.accessioned2018-12-20T19:41:55Z
dc.date.available2018-12-20T19:41:55Z
dc.date.issued2012-02-09
dc.description.abstractNeuronal optical excitation can provide non-contacting tools to explore brain circuitry and a durable stimulation interface for cardiac pacing and visual as well as auditory sensory neuronal stimulation. To obtain accurate absorption spectra, we scan the transmission of neurons in cell culture medium, and normalize it by subtracting out the absorption spectrum of the medium alone. The resulting spectra show that the main neuronal absorption peaks are in the 3000- 6000nm band, although there is a smaller peak near 1450nm. By coupling the output of a 3μm interband cascade laser (ICL) into a mid-IR fluorozirconate fiber, we can effectively deliver more than 1J/cm² photon intensity to the excitation site for neuronal stimulation.en_US
dc.description.urihttps://www.spiedigitallibrary.org/conference-proceedings-of-spie/8207/1/Neuron-absorption-study-and-mid-IR-optical-excitations/10.1117/12.909561.full?SSO=1en_US
dc.format.extent7 pagesen_US
dc.genreconference papers and proceedingsen_US
dc.identifierdoi:10.13016/m2wyxy-stwf
dc.identifier.citationDingkai Guo, Dingkai Guo, Xing Chen, Xing Chen, Shilpa Vadala, Shilpa Vadala, Jennie Leach, Jennie Leach, Yordan Kostov, Yordan Kostov, William W. Bewley, William W. Bewley, Chul-Soo Kim, Chul-Soo Kim, Mijin Kim, Mijin Kim, Chadwick L. Canedy, Chadwick L. Canedy, Charles D. Merritt, Charles D. Merritt, Igor Vurgaftman, Igor Vurgaftman, Jerry R. Meyer, Jerry R. Meyer, Fow-Sen Choa, Fow-Sen Choa, "Neuron absorption study and mid-IR optical excitations", Proc. SPIE 8207, Photonic Therapeutics and Diagnostics VIII, 82075O (9 February 2012); doi: 10.1117/12.909561;en_US
dc.identifier.urihttps://doi.org/10.1117/12.909561
dc.identifier.urihttp://hdl.handle.net/11603/12340
dc.language.isoen_USen_US
dc.publisherSPIEen_US
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Chemical, Biochemical & Environmental Engineering Department Collection
dc.relation.ispartofUMBC Faculty Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.rights© (2012) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). One print or electronic copy may be made for personal use only. Systematic reproduction
dc.subjectmid-infrareden_US
dc.subjectneuron optical excitationen_US
dc.titleNeuron absorption study and mid-IR optical excitationsen_US
dc.typeTexten_US

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