Real-Time Direct Measurement of Human Liver Allograft Temperature from Recovery to Transplantation

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dc.contributor.authorVilla, Rosa
dc.contributor.authorFondevila, Constantino
dc.contributor.authorErill, Ivan
dc.contributor.authorGuimera, Anton
dc.contributor.authorBombuy, Ernest
dc.contributor.authorGomez-Suarez, Cristina
dc.contributor.authorSacristan, Juan Carlos
dc.contributor.authorGarcıa-Valdecasas, Juan Carlos
dc.date.accessioned2021-03-09T17:32:06Z
dc.date.available2021-03-09T17:32:06Z
dc.date.issued2006-02-15
dc.description.abstractTemperature is a key parameter in organ preservation that has been consistently linked to primary nonfunction (PNF). In this communication, and for the first time anywhere, continued and direct measurements of human liver intraparenchymal temperatures are reported in six clinical cases of orthotopic liver transplantations (OLT). These measurements cover the entire transplantation procedure and include the full transport phase. In contrast with long-held beliefs, these data demonstrate that liver allograft temperatures reach and stabilize at near 0°C, instead of 4°C, during transport using standard protocols. Furthermore, these low temperatures do not appear to contribute to graft failure when negative factors such as long preservation, the presence of hepatic steatosis, or advanced donor age are present. The clinical and experimental implications of these findings, together with other relevant elements derived from the direct and continuous monitoring of human liver allograft intraparenchymal temperatures, are discussed.en_US
dc.description.sponsorshipWe are indebted to Enric Calderon and Luı´s Sanchez for their excellent technical assistance, and also to Chuck Simmons for his revision of this manuscript.en_US
dc.description.urihttps://journals.lww.com/transplantjournal/Fulltext/2006/02150/Real_Time_Direct_Measurement_of_Human_Liver.31.aspxen_US
dc.format.extent4 pagesen_US
dc.genrejournal articlesen_US
dc.identifierdoi:10.13016/m2p9xl-8xip
dc.identifier.citationCite Villa, Rosa; Fondevila, Constantino; Erill, Ivan et al., Real-Time Direct Measurement of Human Liver Allograft Temperature from Recovery to Transplantation, Transplantation: February 15, 2006 - Volume 81 - Issue 3 - p 483-486 doi: 10.1097/01.tp.0000195903.12999.bcen_US
dc.identifier.urihttps://doi.org/10.1097/01.tp.0000195903.12999.bc
dc.identifier.urihttp://hdl.handle.net/11603/21116
dc.language.isoen_USen_US
dc.publisherWolters Kluwer Healthen_US
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Biological Sciences Department Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.subjectliveren_US
dc.subjectmonitoringen_US
dc.subjecttemperatureen_US
dc.subjecttransporten_US
dc.subjectviabilityen_US
dc.titleReal-Time Direct Measurement of Human Liver Allograft Temperature from Recovery to Transplantationen_US
dc.typeTexten_US

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