Comparative population genomics of Arctic sled dogs reveals a deep and complex history
| dc.contributor.author | Smith, Tracy | |
| dc.contributor.author | Srikanth, Krishnamoorthy | |
| dc.contributor.author | Huson, Heather Jay | |
| dc.date.accessioned | 2024-09-24T08:59:17Z | |
| dc.date.available | 2024-09-24T08:59:17Z | |
| dc.date.issued | 2024-08-28 | |
| dc.description.abstract | Recent evidence demonstrates genomic and morphological continuity in the Arctic ancestral lineage of dogs. Here, we use the Siberian Husky to investigate the genomic legacy of the northeast Eurasian Arctic lineage and model the deep population history using genome-wide SNPs. Utilizing ancient dog calibrated molecular clocks, we found that at least two distinct lineages of Arctic dogs existed in ancient Eurasia at the end of the Pleistocene. This pushes back the origin of sled dogs in the northeast Siberian Arctic with humans likely intentionally selecting dogs to perform different functions and keeping breeding populations that overlap in time and space relatively reproductively isolated. In modern Siberian Huskies, we found significant population structure based on how they are used by humans, recent European breed introgression in about half of the dogs that participate in races, moderate levels of inbreeding, and fewer potentially harmful variants in populations under strong selection for form and function (Show, Sled-Show, and Racing populations of Siberian Huskies). As the struggle to preserve unique evolutionary lineages while maintaining genetic health intensifies across pedigreed dogs, understanding the genomic history to guide policies and best practices for breed management is crucial to sustain these ancient lineages and their unique evolutionary identity. | |
| dc.description.sponsorship | This work was supported by the University of Maryland Baltimore County College of Natural and Mathematical Sciences (Excellence Award 2021-22; T.A.S.), Neogen Genomics (H.J.H.), and the Siberian Husky Club of America (H.J.H.). | |
| dc.description.uri | https://academic.oup.com/gbe/advance-article/doi/10.1093/gbe/evae190/7742946 | |
| dc.format.extent | 21 pages | |
| dc.genre | journal articles | |
| dc.identifier | doi:10.13016/m2eyci-amuo | |
| dc.identifier.citation | Smith, Tracy A, Krishnamoorthy Srikanth, and Heather Jay Huson. “Comparative Population Genomics of Arctic Sled Dogs Reveals a Deep and Complex History.” Genome Biology and Evolution, August 28, 2024, evae190. https://doi.org/10.1093/gbe/evae190. | |
| dc.identifier.uri | https://doi.org/10.1093/gbe/evae190 | |
| dc.identifier.uri | http://hdl.handle.net/11603/36313 | |
| dc.language.iso | en_US | |
| dc.publisher | Oxford University Press | |
| dc.relation.isAvailableAt | The University of Maryland, Baltimore County (UMBC) | |
| dc.relation.ispartof | UMBC Faculty Collection | |
| dc.relation.ispartof | UMBC Biological Sciences Department | |
| dc.rights | Attribution-NonCommercial 4.0 International CC BY-NC 4.0 Deed | |
| dc.rights.uri | https://creativecommons.org/licenses/by-nc/4.0/ | |
| dc.title | Comparative population genomics of Arctic sled dogs reveals a deep and complex history | |
| dc.type | Text | |
| dcterms.creator | https://orcid.org/0000-0003-3579-9679 |