ECO, the Evidence & Conclusion Ontology: community standard for evidence information

dc.contributor.authorGiglio, Michelle
dc.contributor.authorTauber, Rebecca
dc.contributor.authorNadendla, Suvarna
dc.contributor.authorMunro, James
dc.contributor.authorOlley, Dustin
dc.contributor.authorBall, Shoshannah
dc.contributor.authorMitraka, Elvira
dc.contributor.authorSchriml, Lynn M
dc.contributor.authorGaudet, Pascale
dc.contributor.authorHobbs, Elizabeth T
dc.contributor.authorErill, Ivan
dc.contributor.authorSiegele, Deborah A
dc.contributor.authorHu, James C
dc.contributor.authorMungall, Chris
dc.contributor.authorChibucos, Marcus C
dc.date.accessioned2022-04-05T16:05:04Z
dc.date.available2022-04-05T16:05:04Z
dc.date.issued2019-01-08
dc.description.abstractThe Evidence and Conclusion Ontology (ECO) contains terms (classes) that describe types of evidence and assertion methods. ECO terms are used in the process of biocuration to capture the evidence that supports biological assertions (e.g. gene product X has function Y as supported by evidence Z). Capture of this information allows tracking of annotation provenance, establishment of quality control measures and query of evidence. ECO contains over 1500 terms and is in use by many leading biological resources including the Gene Ontology, UniProt and several model organism databases. ECO is continually being expanded and revised based on the needs of the biocuration community. The ontology is freely available for download from GitHub (https://github.com/evidenceontology/) or the project’s website (http://evidenceontology.org/). Users can request new terms or changes to existing terms through the project’s GitHub site. ECO is released into the public domain under CC0 1.0 Universal.en_US
dc.description.sponsorshipThe ECO project gratefully acknowledges contributions from: multiple members of the Gene Ontology Consortium and several Model Organism Databases, your feedback and contributions continually enrich the ECO resource as a whole; the OBI development team, in particular Bjoern Peters, James Overton, Christian J. Stoeckert, Jr. and Jie Zheng, for help adding terms to OBI; the many individuals who contributed to the specific term development projects described above; Matt Brush for help on ECO design patterns; Andrew Su, Benjamin Good, Sebastian Burgstaller-Muehlbacher and Andra Waagmeester for integration of ECO into Wikidata; Amrita Madabushi for her help in outreach to prospective interns; the past ECO interns Kimuel Villanova, Shayan Hajiabadi, Marina Grekova, Francis Pobelete and Binika Chunara; our Scientific Advisory Board Bjoern Peters, Claire O’Donovan, and Ramona Walls; and finally, all of the people who have submitted term requests or comments and thus contributed to ECO. National Science Foundation Division of Biological Infrastructure [1458400]; National Institutes of Health [R01GM089636, U41HG008735]. Funding for open access charge: National Science Foundation [1458400].en_US
dc.description.urihttps://academic.oup.com/nar/article/47/D1/D1186/5165344en_US
dc.format.extent9 pagesen_US
dc.genrejournal articlesen_US
dc.identifierdoi:10.13016/m2lnce-opdu
dc.identifier.citationMichelle Giglio, Rebecca Tauber, Suvarna Nadendla, James Munro, Dustin Olley, Shoshannah Ball, Elvira Mitraka, Lynn M Schriml, Pascale Gaudet, Elizabeth T Hobbs, Ivan Erill, Deborah A Siegele, James C Hu, Chris Mungall, Marcus C Chibucos, ECO, the Evidence & Conclusion Ontology: community standard for evidence information, Nucleic Acids Research, Volume 47, Issue D1, 08 January 2019, Pages D1186–D1194, https://doi.org/10.1093/nar/gky1036en_US
dc.identifier.urihttps://doi.org/10.1093/nar/gky1036
dc.identifier.urihttp://hdl.handle.net/11603/24524
dc.language.isoen_USen_US
dc.publisherOxford University Pressen_US
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Biological Sciences Department Collection
dc.relation.ispartofUMBC Faculty Collection
dc.rightsThis work was written as part of one of the author's official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law.en_US
dc.rightsPublic Domain Mark 1.0*
dc.rights.urihttp://creativecommons.org/publicdomain/mark/1.0/*
dc.titleECO, the Evidence & Conclusion Ontology: community standard for evidence informationen_US
dc.typeTexten_US
dcterms.creatorhttps://orcid.org/0000-0002-7280-7191en_US

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