Germ Cells and Epigenetics

Simple item page
dc.contributor.authorWagner, Cynthia R.
dc.date.accessioned2019-05-23T15:45:24Z
dc.date.available2019-05-23T15:45:24Z
dc.description.abstractAll multicellular organisms begin life as a single cell, the zygote, created by the union of two germ cells, an oocyte and a sperm. Although scientists have understood for decades that the quantity of DNA an individual inherits from each parent is equivalent, a 1984 discovery by McGrath and Solter revealed that these genes are used differently depending on whether the genes are inherited from the mother or the father (McGrath & Solter 1984). These two scientists used the technique of nuclear transplantation — when the nucleus of one cell is removed and placed into another cell — and asked two questions: Can mouse embryos derived from the nuclei of two oocytes create a viable embryo? What about nuclei from two sperm? They found that these uniparental embryos were not viable and concluded that both maternal and paternal nuclear genomes are necessary for proper embryonic development. But why?en_US
dc.description.urihttps://www.nature.com/scitable/topicpage/germ-cells-and-epigenetics-14426688en_US
dc.genrejournal articlesen_US
dc.identifierdoi:10.13016/m2cn4s-i7kc
dc.identifier.citationWagner, C. R. (2010) Germ Cells and Epigenetics. Nature Education 3(9):64en_US
dc.identifier.urihttp://hdl.handle.net/11603/13927
dc.language.isoen_USen_US
dc.publisherNature Educationen_US
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Biological Sciences Department Collection
dc.relation.ispartofUMBC Faculty Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.subjectepigeneticsen_US
dc.subjectgerm cellsen_US
dc.subjectzygoteen_US
dc.subjectembryonic developmenten_US
dc.titleGerm Cells and Epigeneticsen_US
dc.typeTexten_US

Files

License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
2.56 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

UMBC Biological Sciences Department
UMBC Faculty Collection