On the evolution of the standard amino-acid alphabet

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https://pubmed.ncbi.nlm.nih.gov/16515719/

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https://doi.org/10.1186/gb-2006-7-1-102
 http://hdl.handle.net/11603/28750

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UMBC Biological Sciences Department
UMBC Faculty Collection
UMBC Individualized Study Program (INDS)

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Date

2006-02-01

Type of Work

journal articles
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Citation of Original Publication

Lu, Y., Freeland, S. On the evolution of the standard amino-acid alphabet. Genome Biol 7, 102 (2006). https://doi.org/10.1186/gb-2006-7-1-102

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Subjects

genetic code
Selenocysteine
standard amino acid
prebiotic chemistry
standard genetic code

Abstract

Although one standard amino-acid 'alphabet' is used by most organisms on Earth, the evolutionary cause(s) and significance of this alphabet remain elusive. Fresh insights into the origin of the alphabet are now emerging from disciplines as diverse as astrobiology, biochemical engineering and bioinformatics.