The Influence of Stochastic Parameters on Calcium Waves in a Heart Cell
| dc.contributor.author | Brewster, Matthew W. | |
| dc.date.accessioned | 2018-10-26T13:33:56Z | |
| dc.date.available | 2018-10-26T13:33:56Z | |
| dc.date.issued | 2013 | |
| dc.description.abstract | Calcium is a critical component in many cellular functions. It serves many important functions such as signal transduction, contraction of muscles, enzyme function, and maintaining potential difference across excitable membranes. In this study we examine calcium waves in a heart cell and how they diffuse. Calcium sparks are intracellular release events which are important in converting electrical stimuli into mechanical responses. We investigate the effects of a stochastic spatially uniform ux density term as well as of a stochastic spatially varying ux density term. We hypothesize that having a stochastic ux density term is more physiologically accurate. We use an array of statistical techniques as well as parallel computing to facilitate the large number of simulation runs. | en |
| dc.description.sponsorship | The facility is supported by the U.S. National Science Foundation through the MRI program (grant nos. CNS-0821258 and CNS{1228778) and the SCREMS program (grant no. DMS-0821311), with additional substantial support from the University of Maryland, Baltimore County (UMBC). | en |
| dc.description.uri | https://userpages.umbc.edu/~gobbert/papers/BrewsterThesis2014.pdf | en |
| dc.format.extent | 20 pages | en |
| dc.genre | senior thesis | en |
| dc.identifier | doi:10.13016/M2J09W798 | |
| dc.identifier.uri | http://hdl.handle.net/11603/11741 | |
| dc.language.iso | en | en |
| dc.relation.isAvailableAt | The University of Maryland, Baltimore County (UMBC) | |
| dc.relation.ispartof | UMBC Mathematics Department Collection | |
| dc.relation.ispartof | UMBC Student Collection | |
| dc.rights | This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author. | |
| dc.subject | Stochastic Parameters | en |
| dc.subject | Calcium Waves | en |
| dc.subject | Heart Cell | en |
| dc.subject | contraction of muscles | en |
| dc.subject | enzyme | en |
| dc.subject | UMBC High Performance Computing Facility (HPCF) | en |
| dc.title | The Influence of Stochastic Parameters on Calcium Waves in a Heart Cell | en |
| dc.type | Text | en |