Stevenson Scholar Exchange @ Stevenson University
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Our institutional repository, Stevenson Scholar Exchange, is a digital, online archive of scholarly, academic, professional, and creative work by Stevenson community members. We are very excited about gathering and celebrating the variety of work being produced by our community members across all departments and schools. Items submitted to Stevenson Scholar Exchange are publicly available online to all internet users.
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Browsing Stevenson Scholar Exchange @ Stevenson University by Type "Journal Article"
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Item A conceptual model of systems thinking leadership in community colleges(Systemic Practice and Action Research, 2015-08) Davis, Anne Powel; Dent, Eric B.; Wharff, Deborah M.The pluralistic and often competing goals of myriad constituents, the changing demographics of students, the uncertainty of funding, and the growing demands for accountability from stakeholders have increased the complexity of systems which community college leaders must manage. Emerging from the recent literature on community colleges is a call for new models of leadership in the context of leading in an increasingly uncertain and complex environment. Systems thinking offers a means to help leaders respond to these growing organizational complexities and move leadership from a traditional bureaucratic model to a more adaptive model. A systematic review of literature on systems thinking’s application to organizational performance in higher education was bolstered with evidence from healthcare. Findings revealed three reoccurring ways in which leaders apply systems thinking processes for improving organizational performance. A conceptual model for systems thinking leadership is proposed in which the three processes, characterized as discovery, framing, and action, can be enacted either individually or sequentially for enhancing organizational performance. The model draws upon boundary critique, critical systems thinking, systemic intervention, total systems intervention, systems dynamics, soft systems methodology, complexity theory and complex adaptive systems, yet uses language more readily identifiable to community college practitioners.Item The joy of pain and the pain of joy: In-group identification predicts schadenfreude and gluckschmerz following rival groups' fortunes(Motivation & Emotion, 2015-04) Hoogland, Charles; Schurtz, D. Ryan; Cooper, Chelsea; Combs, David; Brown, Edward; Smith, Richard; PsychologyFour studies examined how in-group identification in the domain of sports is associated with schadenfreude in reaction to another group's suffering or gluckschmerz in reaction to another group's good fortune. Schadenfreude increased as a function of in-group identification when the outgroup was a rival team rather than a non-rival team in Study 1. Study 2 showed that those who experience schadenfreude at learning of an outgroup player's injury will also tend to feel gluckschmerz when they learn of the player's recovery. Studies 3 and 4 replicated and extended these findings for both schadenfreude and gluckschmerz, and showed that neither the degree of severity of an injury nor the level of physical pain associated with the injury moderated the link between identification and both schadenfreude and gluckschmerz. Mediation analyses indicated that perceived in-group gain or loss, deservedness, and dislike were prime mediators of links between in-group identification and both emotions.Item A matrix-focused structure-activity and binding site flexibility study of quinolinol inhibitors of botulinum neurotoxin serotype A(Bioorganic & Medicinal Chemistry Letters, 2017-02-01) Harrell, William A. Jr.; Vieira, Rebecca C.; Ensel, Susan M.; Montgomery, Vicki; Guernieri, Rebecca; Eccard, Vanessa S.; Campbell, Yvette; Roxas-Duncan, Virginia; Cardellina, John H. II; Webb, Robert P.; Smith, Leonard A.; ChemistryOur initial discovery of 8-hydroxyquinoline inhibitors of BoNT/A and separation/testing of enantiomers of one of the more active leads indicated considerable flexibility in the binding site. We designed a limited study to investigate this flexibility and probe structure-activity relationships; utilizing the Betti reaction, a 36 compound matrix of quinolinol BoNT/A LC inhibitors was developed using three 8-hydroxyquinolines, three heteroaromatic amines, and four substituted benzaldehydes. This study has revealed some of the most effective quinolinol-based BoNT/A inhibitors to date, with 7 compounds displaying IC50 values ⩽1μM and 11 effective at ⩽2μM in an ex vivo assay.Item A Qualitative Analysis of the Experience of Female Chinese American Church Leaders: Associations with Gender Role, Culture, and Work-Family Balance(Pastoral Psychology, 2017-10) Wong, Maria; Worthy, Paige; Fung, Joey; Chen, Eva; PsychologyThis qualitative study explored the unique experiences of seven Chinese American female church leaders, providing examples of the barriers they faced as women and those resulting from cultural conflicts, as well as the impact these factors had on their roles in church ministry. Specifically, the findings addressed the impact of gender roles and culture on these leaders' experiences and the extent to which they were able to achieve work-family balance. The study highlighted the challenges of working with a culturally diverse population as well as the struggles these female leaders faced in a male-dominated field. Furthermore, the factors influencing work-family balance were examined along with strategies for avoiding burnout. Taken together, these findings provided insight into the distinctive experiences of female leaders in ministry and the ways in which churches might be able to better provide for these leaders.Item Utilizing Ayurvedic literature for the identification of novel phytochemical inhibitors of botulinum neurotoxin A(Journal of Ethnopharmacology, 2017-02-02) Yalamanchili, Chinni; Manda, Vamshi K.; Chittiboyina, Amar G.; Guernieri, Rebecca L.; Harrell, William A. Jr.; Webb, Robert P.; Smith, Leonard A.; Khan, Ikhlas A.; ChemistryEthnopharmacological relevance Ayurveda, an ancient holistic system of health care practiced on the Indian subcontinent, utilizes a number of multi-plant formulations and is considered by many as a potential source for novel treatments, as well as the identification of new drugs. Our aim is to identify novel phytochemicals for the inhibition of bacterial exotoxin, botulinum neurotoxin A (BoNT/A) based on Ayurvedic literature. BoNT/A is released by Clostridium species, which when ingested, inhibits the release of acetylcholine by concentrating at the neuromuscular junction and causes flaccid paralysis, resulting in a condition termed as botulism, and may also lead to death due to respiratory arrest. Results From the docking scores and structural diversity, nine compounds including acoric acid 1, three flavonoids, three coumarins derivatives, one kava lactone were selected and screened using an in vitro HPLC-based protease assay. The bioassay results showed that several compounds possess BoNT/A LC inhibition of 50–60% when compared to positive controls NSC 84094 and CB7967495 (80–95%). Conclusion Further testing of the active compounds identified from Ayurvedic literature and structure-activity studies of acoric acid 1 using more sensitive bioassays is under way. The identification of acoric acid 1, a novel scaffold against BoNT/A, exemplifies the utility of Ayurvedic literature for the discovery of novel drug leads.