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    Dynamic ray tracing for modeling optical cell manipulation

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    oe-18-16-16702.pdf (1.044Mb)
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    https://www.osapublishing.org/oe/abstract.cfm?uri=oe-18-16-16702
    Permanent Link
    https://doi.org/10.1364/OE.18.016702
    http://hdl.handle.net/11603/11626
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    • UMBC Faculty Collection
    • UMBC Mechanical Engineering Department
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    Author/Creator
    Sraj, Ihab
    Szatmary, Alex C.
    Marr, David W. M.
    Eggleton, Charles D.
    Date
    2010-07-23
    Type of Work
    13 pages
    Text
    journal article
    Citation of Original Publication
    Ihab Sraj, Alex C. Szatmary, David W. M. Marr, Charles D. Eggleton , Optics Express Vol. 18, Issue 16, pp. 16702-16714 (2010) ,https://doi.org/10.1364/OE.18.016702
    Rights
    This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
    © 2010 Optical Society of America]. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reserved.
    Subjects
    Cell analysis
    Diode lasers
    Laser trapping
    Numerical approximation and analysis
    UMBC High Performance Computing Facility (HPCF)
    Abstract
    Current methods for predicting stress distribution on a cell surface due to optical trapping forces are based on a traditional ray optics scheme for fixed geometries. Cells are typically modeled as solid spheres as this facilitates optical force calculation. Under such applied forces however, real and non-rigid cells can deform, so assumptions inherent in traditional ray optics methods begin to break down. In this work, we implement a dynamic ray tracing technique to calculate the stress distribution on a deformable cell induced by optical trapping. Here, cells are modeled as three-dimensional elastic capsules with a discretized surface with associated hydrodynamic forces calculated using the Immersed Boundary Method. We use this approach to simulate the transient deformation of spherical, ellipsoidal and biconcave capsules due to external optical forces induced by a single diode bar optical trap for a range of optical powers.


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    Albin O. Kuhn Library & Gallery
    University of Maryland, Baltimore County
    1000 Hilltop Circle
    Baltimore, MD 21250
    www.umbc.edu/scholarworks

    Contact information:
    Email: scholarworks-group@umbc.edu
    Phone: 410-455-3544


    If you wish to submit a copyright complaint or withdrawal request, please email mdsoar-help@umd.edu.