• Optic lobe organization in stomatopod crustacean species possessing different degrees of retinal complexity 

  Lin, Chan; Chou, Alice; Cronin, Thomas W. (Springer Berlin Heidelberg, 2019-12-06)

  Stomatopod crustaceans possess tripartite compound eyes; upper and lower hemispheres are separated by an equatorial midband of several ommatidial rows. The organization of stomatopod retinas is well established, but their ...

• The next generation of biopanning: next gen sequencing improves analysis of bacterial display libraries 

  Stellwagen, Sarah D.; Sarkes, Deborah A.; Adams, Bryn L.; Hunt, Mia A.; Renberg, Rebecca L.; Hurley, Margaret M.; Stratis-Cullum, Dimitra N. (BioMed Central, 2019-12-21)

  Background: Bacterial surface display libraries are a popular tool for novel ligand discovery due to their ease of manipulation and rapid growth rates. These libraries typically express a scaffold protein embedded within ...

• A Novel Genus of Actinobacterial Tectiviridae 

  Caruso, Steven M.; deCarvalho, Tagide N.; Huynh, Anthony; Morcos, George; Kuo, Nansen; Parsa, Shabnam; Erill, Ivan (MDPI, 2019-12-07)

  Streptomyces phages WheeHeim and Forthebois are two novel members of the Tectiviridaefamily. These phages were isolated on cultures of the plant pathogen Streptomyces scabiei, known for its worldwide economic impact on ...

• Effect of Diet on the Enteric Microbiome of the Wood-Eating Catfish Panaque nigrolineatus 

  McDonald, Ryan C.; Watts, Joy E. M.; Schreier, Harold J (Frontiers, 2019-11-29)

  Wood is consistently found in high levels in the gastrointestinal tract of the Amazonian catfish Panaque nigrolineatus, which, depending on environmental conditions, can switch between xylivorous and detritivorous dietary ...

• Why do females sing?—pair communication and other song functions in eastern bluebirds 

  Rose, Evangeline M.; Coss, Derek A.; Haines, Casey D.; Danquah, Sheridan A.; Studds, Colin E.; Omland, Kevin E. (Oxford University Press, 2019-08-03)

  Female bird song has been underappreciated and understudied, especially in temperate species. Birdsong was originally thought to be a trait used primarily by male songbirds for mate attraction and male/male contest. However, ...

• Survival of the fittest: how myeloid‑derived suppressor cells survive in the inhospitable tumor microenvironment 

  Ostrand‑Rosenberg, Suzanne; Beury, Daniel W.; Parker, Katherine H.; Horn, Lucas A. (Springer Berlin Heidelberg, 2019-09-09)

  Myeloid-derived suppressor cells (MDSC) are present in most cancer patients where they are signifcant contributors to the immune suppressive tumor microenvironment (TME). The TME is a hostile locale due to defciencies in ...

• Myeloid-Derived Suppressor Cells: Not Only in Tumor Immunity 

  Pawelec, Graham; Verschoor, Chris P; Ostrand-Rosenberg, Suzanne (Frontiers Media S.A., 2019-05-15)

  Since the realization that immature myeloid cells are powerful modulators of the immune response, many studies on “myeloid-derived suppressor cells” (MDSCs) have documented their ability to promote tumor progression in ...

• Long-Wavelength Reflecting Filters Found in the Larval Retinas of One Mantis Shrimp Family (Nannosquillidae) 

  Feller, Kathryn D.; Wilby, David; Jacucci, Gianni; Vignolini, Silvia; Mantell, Judith; Wardill, Trevor J.; Cronin, Thomas W.; Roberts, Nicholas W. (Elsevier B.V., 2019-09-23)

  Both vertebrates and invertebrates commonly exploit photonic structures adjacent to their photoreceptors for visual benefits. For example, use of a reflecting structure (tapetum) behind the retina increases photon capture, ...

• Differential Regulation of T-cell Immunity and Tolerance by Stromal Laminin Expressed in the Lymph Node 

  Simon, Thomas; Li, Lushen; Wagner, Chelsea; Zhang, Tianshu; Saxena, Vikas; Brinkman, C. Colin; Tostanoski, Lisa H; Ostrand-Rosenberg, Suzanne; Jewell, Chris; Shea-Donohue, Terez; Hippen, Keli; Blazar, Bruce; Abdi, Reza; Bromberg, Jonathan S (Wolters Kluwer Health, 2019-10-01)

  Background. Stromal laminins α4 and α5 are differentially regulated in transplant tolerance and immunity, respectively, resulting in altered T-cell trafficking. We hypothesized that laminins directly regulated T-cell ...

• Lisinopril preserves physical resilience and extends life span in a genotype-specific manner in Drosophila melanogaster 

  Gabrawy, Mariann M.; Campbell, Sarah; Carbone, Mary Anna; Morozova, Tatiana V.; Arya, Gunjan H.; Turlapati, Lavanya B.; Walston, Jeremy D.; Starz-Gaiano, Michelle; Everett, Logan; Mackay, Trudy F. C.; Leips, Jeff; Abadir, Peter M. (Oxford University Press, 2019-06-14)

  Physical resiliency declines with age and comorbid conditions. In humans, Angiotensin Converting Enzyme (ACE) has been associated with attenuation of the decline in physical performance with age. ACE-inhibitor (ACEi) ...

• Functionally Significant Features in the 5' Untranslated Region of the ABCA1 Gene and Their Comparison in Vertebrates 

  Dvorak, Pavel; Leupen, Sarah; Soucek, Pavel (MDPI, 2019-06-21)

  Single nucleotide polymorphisms located in 5' untranslated regions (50UTRs) can regulate gene expression and have clinical impact. Recognition of functionally significant sequences within 5' UTRs is crucial in next-generation ...

• LUX ARRHYTHMO mediates crosstalk between the circadian clock and defense in Arabidopsis 

  Zhang, Chong; Gao, Min; Seitz, Nicholas C.; Angel, William; Hallworth, Amelia; Wiratan, Linda; Darwish, Omar; Alkharouf, Nadim; Dawit, Teklu; Lin, Daniela; Egoshi, Riki; Wang, Xiping; McClung, C. Robertson; Lu, Hua (Springer Nature Limited, 2019-06-11)

  The circadian clock is known to regulate plant innate immunity but the underlying mechanism of this regulation remains largely unclear. We show here that mutations in the core clock component LUX ARRHYTHMO (LUX) disrupt ...

• Rgma-Induced Neo1 Proteolysis Promotes Neural Tube Morphogenesis 

  Brown, Sharlene; Jayachandran, Pradeepa; Negesse, Maraki; Olmo, Valerie; Vital, Eudorah; Brewster, Rachel (Society for NeuroScience, 2019-09-18)

  Neuroepithelial cell (NEC) elongation is one of several key cell behaviors that mediate the tissue-level morphogenetic movements that shape the neural tube (NT), the precursor of the brain and spinal cord. However, the ...

• Mapping of ribosomal protein genes by in vitro protein synthesis using DNA fragments of lambda fus3 transducing phage DNA as templates 

  Lindahl, Lasse; Post, Leonard; Zengel, Janice; Gilbert, Scott F.; Strycharz, William A.; Nomura, Masayasu (1977-10-25)

  hfus3 (or hfus2) transducing phage stimulates the synthesis of 27 ribosomal proteins, elongation factors EF-Tu and EF-G, and RNA polymerase subunit (Y in ultraviolet-irradiated Escherichia roli cells (see a preceding ...

• Cluster of genes in Escherichia coli for ribosomal proteins, ribosomal RNA, and RNA polymerase subunits 

  Lindahl, L.; Jaskunas, S. R.; Dennis, P. P.; Nomura, M. (National Academy of Sciences, 1975-07-01)

  This work was supported in part by the College of Agriculture and Life Sciences, University of Wisconsin, and by grants from the National Science Foundation (GB31086) and the National Institute of General Medical Sciences ...

• Specialized transducing phages for ribosomal protein genes of Escherichia coli 

  Jaskunas, S. R.; Lindahl, L.; Nomura, M. (National Academy of Sciences, 1975-01-01)

  Specialized lambda transducing phages have been isolated carrying approximately half the ribosomal protein genes of E. coli. These phages carry regions of the bacterial chromosome between aroE and fus. The ribosomal protein ...

• The small and large ribosomal subunits depend on each other for stability and accumulation 

  Gregory, Brian; Rahman, Nusrat; Bommakanti, Ananth; Shamsuzzaman, Md; Thapa, Mamata; Lescure, Alana; Zengel, Janice M.; Lindahl, Lasse (Life Science Alliance, 2019-03-05)

  The 1:1 balance between the numbers of large and small ribosomal subunits can be disturbed by mutations that inhibit the assembly of only one of the subunits. Here, we have investigated if the cell can counteract an imbalance ...

• Analysis of cell cycle parameters during the transition from unhindered growth to ribosomal and translational stress conditions 

  Shamsuzzaman, Md; Bommakanti, Ananth; Zapinsky, Aviva; Rahman, Nusrat; Pascual, Clarence; Lindahl, Lasse (PLOS, 2017-10-13)

  Abrogation of ribosome synthesis (ribosomal stress) leads to cell cycle arrest. However, the immediate cell response to cessation of ribosome formation and the transition from normal cell proliferation to cell cycle arrest ...

• The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel 

  Wekselman, Itai; Zimmerman, Ella; Davidovich, Chen; Lindahl, Lasse; Zengel, Janice M.; Yonath, Ada (Cell Press, 2017-08-01)

  Erythromycin is a clinically useful antibiotic that binds to an rRNA pocket in the ribosomal exit tunnel. Commonly, resistance to erythromycin is acquired by alterations of rRNA nucleotides that interact with the drug. ...

• The extended loops of ribosomal proteins uL4 and uL22 of Escherichia coli contribute to ribosome assembly and protein translation 

  Lawrence, Marlon G.; Shamsuzzaman, M.d.; Kondopaka, Maithri; Pascual, Clarence; Zengel, Janice M.; Lindahl, Lasse (Oxford University Press, 2016-06-01)

  Nearly half of ribosomal proteins are composed of a domain on the ribosome surface and a loop or extension that penetrates into the organelle's RNA core. Our previous work showed that ribosomes lacking the loops of ribosomal ...

View more