Recent Advances in Wearable Sweat Sensor Development
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Date
2025
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Citation of Original Publication
Zhang, Tao, Giraso Keza Monia Kabandana, John A. Terrell, Hui Chen, and Chengpeng Chen. ?Recent Advances in Wearable Sweat Sensor Development.? WIREs Nanomedicine and Nanobiotechnology 17, no. 1 (2025): e70006. https://doi.org/10.1002/wnan.70006.
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This is the peer reviewed version of the following article: Zhang, Tao, Giraso Keza Monia Kabandana, John A. Terrell, Hui Chen, and Chengpeng Chen. ?Recent Advances in Wearable Sweat Sensor Development.? WIREs Nanomedicine and Nanobiotechnology 17, no. 1 (2025): e70006. https://doi.org/10.1002/wnan.70006, which has been published in final form at https://doi.org/10.1002/wnan.70006. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley?s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
Abstract
Wearable sweat sensors for detecting biochemical markers have emerged as a transformative research area, with the potential to revolutionize disease diagnosis and human health monitoring. Since 2016, a substantial body of pioneering and translational work on sweat biochemical sensors has been reported. This review aims to provide a comprehensive summary of the current state-of-the-art in the field, offering insights and perspectives on future developments. The focus is on wearable microfluidic platforms for sweat collection and delivery and the analytical chemistry applicable to wearable devices. Various microfluidic technologies, including those based on synthetic polymers, paper, textiles, and hydrogels, are discussed alongside diverse detection methods such as electrochemistry and colorimetry. Both the advantages and current limitations of these technologies are critically examined. The review concludes with our perspectives on the future of wearable sweat sensors, with the goal of inspiring new ideas, innovations, and technical advancements to further the development and practical application of these devices in promoting human health.